Tursiops truncatus      Spindle apparatus


※ Spindle apparatus introduction

    The spindle is an important structure when cells divide. Phase separation promotes the concentration of molecules into the droplets, thereby promoting biochemical reactions. Some protein mixtures undergo a phase change to form droplets that concentrate actin to promote F-actin assembly in vitro. In addition, studies have shown that the phase transition of spindle regulatory protein BuGZ concentrates tubulin and promotes MT polymerizationbinds to tubulin and promotes spindle assembly (1).

Reference
1. Jiang, H., Wang, S., Huang, Y., He, X., Cui, H., Zhu, X., & Zheng, Y. (2015) Phase transition of spindle-associated protein regulate spindle apparatus assembly. Cell, 163(1), 108-122. PMID: 26388440


There are 17 genes.  Reviewed (0 or Unreviewed (17

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Tut-1002
ENSTTRG00000009624.1
A0A2U3V7Z1
CKAP2
2
LLPS-Tut-2427
ENSTTRG00000005433.1
A0A2U3V009
CLTB
3
LLPS-Tut-1307
ENSTTRG00000012102.1
A0A2U3UZK9
DYRK3
4
LLPS-Tut-0292
ENSTTRG00000013736.1
A0A2U3V6W2
HAUS3
5
LLPS-Tut-2307
ENSTTRG00000001772.1
A0A2U4BB48
HAUS6
6
LLPS-Tut-2095
ENSTTRG00000016429.1
A0A2U4AQJ1
KAT14
7
LLPS-Tut-0153
ENSTTRG00000011017.1
A0A2U3VAQ1
MAD2L1
8
LLPS-Tut-1303
ENSTTRG00000010078.1
A0A2U4AZN8
MAD2L2
9
LLPS-Tut-0127
ENSTTRG00000016253.1
A0A2U4B5L0
MAPK6
10
LLPS-Tut-1330
ENSTTRG00000014809.1
A0A2U4CLR0
MAPRE1
11
LLPS-Tut-0246
ENSTTRG00000009901.1
A0A2U4BQ89
MARVELD1
12
LLPS-Tut-0544
ENSTTRG00000011909.1
A0A2U4BJL7
MKNK1
13
LLPS-Tut-1672
ENSTTRG00000002946.1
A0A2U4CGI1
MSN
14
LLPS-Tut-0645
ENSTTRG00000007813.1
A0A2U4C5B4
RANBP9
15
LLPS-Tut-0403
ENSTTRG00000012451.1
A0A2U4A7N4
RBPMS
16
LLPS-Tut-0518
ENSTTRG00000017034.1
A0A2U4CLM2
SPAG4
17
LLPS-Tut-0824
ENSTTRG00000005630.1
A0A2U4C0T8
SUN2