Schizosaccharomyces japonicus      Spindle apparatus


※ Spindle apparatus introduction

    The spindle is an important structure when cells divide. Phase separation promotes the concentration of molecules into the droplets, thereby promoting biochemical reactions. Some protein mixtures undergo a phase change to form droplets that concentrate actin to promote F-actin assembly in vitro. In addition, studies have shown that the phase transition of spindle regulatory protein BuGZ concentrates tubulin and promotes MT polymerizationbinds to tubulin and promotes spindle assembly (1).

Reference
1. Jiang, H., Wang, S., Huang, Y., He, X., Cui, H., Zhu, X., & Zheng, Y. (2015) Phase transition of spindle-associated protein regulate spindle apparatus assembly. Cell, 163(1), 108-122. PMID: 26388440


There are 11 genes.  Reviewed (0 or Unreviewed (11

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Scj-0610
SJAG_01215
B6K026
SJAG_01215
2
LLPS-Scj-0217
SJAG_01330
B6K0D7
SJAG_01330
3
LLPS-Scj-0413
SJAG_01711
B6JYP6
SJAG_01711
4
LLPS-Scj-1413
SJAG_02074
B6JZN2
SJAG_02074
5
LLPS-Scj-0611
SJAG_03067
B6K384
SJAG_03067
6
LLPS-Scj-0867
SJAG_03073
B6K391
SJAG_03073
7
LLPS-Scj-0382
SJAG_03540
B6K4H9
SJAG_03540
8
LLPS-Scj-0058
SJAG_04400
B6K6R2
SJAG_04400
9
LLPS-Scj-0637
SJAG_04645
B6K7D7
SJAG_04645
10
LLPS-Scj-0183
SJAG_04745
B6K7M9
SJAG_04745
11
LLPS-Scj-0543
SJAG_05019
B6K8E1
SJAG_05019