Sarcophilus harrisii      Spindle apparatus


※ Spindle apparatus introduction

    The spindle is an important structure when cells divide. Phase separation promotes the concentration of molecules into the droplets, thereby promoting biochemical reactions. Some protein mixtures undergo a phase change to form droplets that concentrate actin to promote F-actin assembly in vitro. In addition, studies have shown that the phase transition of spindle regulatory protein BuGZ concentrates tubulin and promotes MT polymerizationbinds to tubulin and promotes spindle assembly (1).

Reference
1. Jiang, H., Wang, S., Huang, Y., He, X., Cui, H., Zhu, X., & Zheng, Y. (2015) Phase transition of spindle-associated protein regulate spindle apparatus assembly. Cell, 163(1), 108-122. PMID: 26388440


There are 35 genes.  Reviewed (0 or Unreviewed (35

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Sah-0087
ENSSHAG00000004306.1
G3VP10
2
LLPS-Sah-1125
ENSSHAG00000014655.1
G3WP84
3
LLPS-Sah-1352
ENSSHAG00000006698.1
G3VX07
4
LLPS-Sah-2147
ENSSHAG00000003657.1
G3VLU6
5
LLPS-Sah-2428
ENSSHAG00000009397.1
G3W646
6
LLPS-Sah-3492
ENSSHAG00000006093.1
G3VV07
7
LLPS-Sah-1436
ENSSHAG00000013174.1
G3WJ52
AURKA
8
LLPS-Sah-3084
ENSSHAG00000012801.1
G3WHU7
CDC6
9
LLPS-Sah-0933
ENSSHAG00000009570.1
G3W6R3
CHAMP1
10
LLPS-Sah-2769
ENSSHAG00000009985.1
G3W865
CKAP2
11
LLPS-Sah-0760
ENSSHAG00000016386.1
G3WV39
CKAP5
12
LLPS-Sah-2994
ENSSHAG00000002452.1
G3VHW7
CLTB
13
LLPS-Sah-0014
ENSSHAG00000017477.1
G3WYV2
DCTN3
14
LLPS-Sah-3374
ENSSHAG00000008277.1
G3W2B2
DPYSL2
15
LLPS-Sah-0688
ENSSHAG00000017827.1
G3X017
DYRK3
16
LLPS-Sah-0354
ENSSHAG00000009483.1
G3W6E8
EZR
17
LLPS-Sah-0950
ENSSHAG00000017430.1
G3WYQ0
GPSM2
18
LLPS-Sah-0190
ENSSHAG00000012083.1
G3WFD4
HAUS3
19
LLPS-Sah-3041
ENSSHAG00000018332.1
G3X1U2
KAT14
20
LLPS-Sah-1142
ENSSHAG00000017296.1
G3WY86
KATNA1
21
LLPS-Sah-0232
ENSSHAG00000018218.1
G3X1F1
KIF11
22
LLPS-Sah-1172
ENSSHAG00000008494.1
G3W308
MAD2L1
23
LLPS-Sah-2213
ENSSHAG00000010168.1
G3W8U2
MAD2L2
24
LLPS-Sah-3068
ENSSHAG00000017091.1
G3WXJ2
MAPK6
25
LLPS-Sah-0701
ENSSHAG00000009466.1
G3W6C7
MAPRE2
26
LLPS-Sah-3135
ENSSHAG00000007412.1
G3VZF1
NCOA4
27
LLPS-Sah-0421
ENSSHAG00000001926.1
G3VG60
RANBP10
28
LLPS-Sah-2752
ENSSHAG00000010114.1
G3W8M6
RBPMS
29
LLPS-Sah-3292
ENSSHAG00000012877.1
G3WI34
SEPT2
30
LLPS-Sah-0293
ENSSHAG00000013896.1
G3WLM7
SMC3
31
LLPS-Sah-0709
ENSSHAG00000007223.1
G3VYT1
SUN3
32
LLPS-Sah-0953
ENSSHAG00000015430.1
G3WRX0
TADA3
33
LLPS-Sah-1357
ENSSHAG00000015305.1
G3WRH1
TPR
34
LLPS-Sah-0555
ENSSHAG00000003998.1
G3VMY9
ZBTB4
35
LLPS-Sah-1029
ENSSHAG00000018513.1
G3X2G6
ZNF207