Rhinopithecus bieti      Spindle apparatus


※ Spindle apparatus introduction

    The spindle is an important structure when cells divide. Phase separation promotes the concentration of molecules into the droplets, thereby promoting biochemical reactions. Some protein mixtures undergo a phase change to form droplets that concentrate actin to promote F-actin assembly in vitro. In addition, studies have shown that the phase transition of spindle regulatory protein BuGZ concentrates tubulin and promotes MT polymerizationbinds to tubulin and promotes spindle assembly (1).

Reference
1. Jiang, H., Wang, S., Huang, Y., He, X., Cui, H., Zhu, X., & Zheng, Y. (2015) Phase transition of spindle-associated protein regulate spindle apparatus assembly. Cell, 163(1), 108-122. PMID: 26388440


There are 34 genes.  Reviewed (0 or Unreviewed (34

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Rhb-0258
ENSRBIG00000035049.1
A0A2K6LF84
2
LLPS-Rhb-1392
ENSRBIG00000038292.1
A0A2K6LZ93
3
LLPS-Rhb-4352
ENSRBIG00000028253.1
A0A2K6KBR7
4
LLPS-Rhb-4474
ENSRBIG00000042270.1
A0A2K6MNP9
CDC6
5
LLPS-Rhb-1407
ENSRBIG00000027109.1
A0A2K6K6F4
CHAMP1
6
LLPS-Rhb-0724
ENSRBIG00000044614.1
A0A2K6N475
CKAP5
7
LLPS-Rhb-4663
ENSRBIG00000020625.1
A0A2K6JZP8
CLTB
8
LLPS-Rhb-3616
ENSRBIG00000034738.1
A0A2K6LDF5
DCTN3
9
LLPS-Rhb-3232
ENSRBIG00000036589.1
A0A2K6LPD2
DLGAP5
10
LLPS-Rhb-3581
ENSRBIG00000038509.1
A0A2K6M0G8
DPYSL2
11
LLPS-Rhb-4543
ENSRBIG00000030013.1
A0A2K6KLL5
DYRK3
12
LLPS-Rhb-4404
ENSRBIG00000009981.1
A0A2K6JSW7
GPSM2
13
LLPS-Rhb-4639
ENSRBIG00000037222.1
A0A2K6LT72
HAUS3
14
LLPS-Rhb-2666
ENSRBIG00000044123.1
A0A2K6N0U3
KAT14
15
LLPS-Rhb-3010
ENSRBIG00000028331.1
A0A2K6KC83
KATNAL1
16
LLPS-Rhb-0550
ENSRBIG00000037663.1
A0A2K6LVQ4
KIF11
17
LLPS-Rhb-2898
ENSRBIG00000027266.1
A0A2K6K6X1
MAD2L2
18
LLPS-Rhb-1167
ENSRBIG00000042693.1
A0A2K6MRI3
MAPRE1
19
LLPS-Rhb-0563
ENSRBIG00000033459.1
A0A2K6L668
MKNK1
20
LLPS-Rhb-3525
ENSRBIG00000041925.1
A0A2K6MME5
MSN
21
LLPS-Rhb-4490
ENSRBIG00000044031.1
A0A2K6N087
MTUS1
22
LLPS-Rhb-1706
ENSRBIG00000043669.1
A0A2K6MXN4
NCOA4
23
LLPS-Rhb-3356
ENSRBIG00000023658.1
A0A2K6K252
PARD3
24
LLPS-Rhb-1046
ENSRBIG00000040697.1
A0A2K6ME00
PRC1
25
LLPS-Rhb-0548
ENSRBIG00000027507.1
A0A2K6K7L9
RANBP9
26
LLPS-Rhb-0630
ENSRBIG00000032420.1
A0A2K6KZU8
SEPT2
27
LLPS-Rhb-1991
ENSRBIG00000043963.1
A0A2K6MZP4
SMC3
28
LLPS-Rhb-0141
ENSRBIG00000044381.1
A0A2K6N2B4
SUN1
29
LLPS-Rhb-1263
ENSRBIG00000012940.1
A0A2K6JUX1
SUN2
30
LLPS-Rhb-2132
ENSRBIG00000031589.1
A0A2K6KUP6
TADA3
31
LLPS-Rhb-0908
ENSRBIG00000019722.1
A0A2K6JYZ8
TMEM201
32
LLPS-Rhb-0611
ENSRBIG00000032437.1
A0A2K6L0H0
TPR
33
LLPS-Rhb-2055
ENSRBIG00000042670.1
A0A2K6MRB2
ZBTB4
34
LLPS-Rhb-1309
ENSRBIG00000030664.1
A0A2K6KPX8
ZNF207