Rattus norvegicus      Spindle apparatus


※ Spindle apparatus introduction

    The spindle is an important structure when cells divide. Phase separation promotes the concentration of molecules into the droplets, thereby promoting biochemical reactions. Some protein mixtures undergo a phase change to form droplets that concentrate actin to promote F-actin assembly in vitro. In addition, studies have shown that the phase transition of spindle regulatory protein BuGZ concentrates tubulin and promotes MT polymerizationbinds to tubulin and promotes spindle assembly (1).

Reference
1. Jiang, H., Wang, S., Huang, Y., He, X., Cui, H., Zhu, X., & Zheng, Y. (2015) Phase transition of spindle-associated protein regulate spindle apparatus assembly. Cell, 163(1), 108-122. PMID: 26388440


There are 37 genes.  Reviewed (0 or Unreviewed (37

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Ran-0231
ENSRNOG00000004479.7
P59241
Aurka
2
LLPS-Ran-2824
ENSRNOG00000015825.7
D4AD76
Aurkc
3
LLPS-Ran-1909
ENSRNOG00000027787.5
D3ZRK7
Cdc6
4
LLPS-Ran-2579
ENSRNOG00000000112.5
B5DEG7
Champ1
5
LLPS-Ran-1105
ENSRNOG00000024650.5
D3ZPD0
Ckap2
6
LLPS-Ran-1740
ENSRNOG00000016067.8
F1M949
Ckap5
7
LLPS-Ran-4543
ENSRNOG00000017506.7
P08082
Cltb
8
LLPS-Ran-0742
ENSRNOG00000014208.5
D4A1B8
Dctn3
9
LLPS-Ran-0079
ENSRNOG00000010721.5
B1WC75
Dlgap5
10
LLPS-Ran-1884
ENSRNOG00000009625.6
P47942
Dpysl2
11
LLPS-Ran-0675
ENSRNOG00000004870.5
Q4V8A3
Dyrk3
12
LLPS-Ran-1471
ENSRNOG00000046028.2
A0A0G2K4Y6
Fam29a
13
LLPS-Ran-0324
ENSRNOG00000011683.5
D4A584
Fes
14
LLPS-Ran-0652
ENSRNOG00000012149.8
D3ZCE5
Gpsm2
15
LLPS-Ran-3884
ENSRNOG00000015255.6
B1WC65
Haus3
16
LLPS-Ran-3612
ENSRNOG00000007160.7
D3ZSX8
Kat14
17
LLPS-Ran-0321
ENSRNOG00000014996.6
Q6E0V2
Katna1
18
LLPS-Ran-0195
ENSRNOG00000056069.1
F1MAB8
Kif11
19
LLPS-Ran-0744
ENSRNOG00000005376.5
D4ACM2
Mad2l1
20
LLPS-Ran-3531
ENSRNOG00000009134.8
D3Z8D9
Mad2l2
21
LLPS-Ran-3065
ENSRNOG00000009381.6
P27704
Mapk6
22
LLPS-Ran-2566
ENSRNOG00000011798.6
Q66HR2
Mapre1
23
LLPS-Ran-2031
ENSRNOG00000010381.7
Q4G050
Mknk1
24
LLPS-Ran-2113
ENSRNOG00000030118.7
O35763
Msn
25
LLPS-Ran-1245
ENSRNOG00000010748.8
Q6IMY1
Mtus1
26
LLPS-Ran-2733
ENSRNOG00000019768.7
B1H215
Ncoa4
27
LLPS-Ran-0293
ENSRNOG00000032437.5
Q9Z340
Pard3
28
LLPS-Ran-3232
ENSRNOG00000018000.6
D3Z7Z5
Ranbp10
29
LLPS-Ran-1200
ENSRNOG00000013328.8
F1M9Y9
Rbpms
30
LLPS-Ran-0367
ENSRNOG00000017952.4
Q91Y81
Sept2
31
LLPS-Ran-0740
ENSRNOG00000014173.7
P97690
Smc3
32
LLPS-Ran-0270
ENSRNOG00000015177.8
D3ZTT7
Sun2
33
LLPS-Ran-1733
ENSRNOG00000008597.6
Q4V8F5
Tada3
34
LLPS-Ran-4426
ENSRNOG00000023152.7
D3ZBW3
Tmem201
35
LLPS-Ran-0333
ENSRNOG00000002394.6
F1MA98
Tpr
36
LLPS-Ran-1429
ENSRNOG00000014689.7
D4A8X0
Zbtb4
37
LLPS-Ran-1220
ENSRNOG00000000236.7
Q498C9
Zfp207