Pongo abelii      Spindle apparatus


※ Spindle apparatus introduction

    The spindle is an important structure when cells divide. Phase separation promotes the concentration of molecules into the droplets, thereby promoting biochemical reactions. Some protein mixtures undergo a phase change to form droplets that concentrate actin to promote F-actin assembly in vitro. In addition, studies have shown that the phase transition of spindle regulatory protein BuGZ concentrates tubulin and promotes MT polymerizationbinds to tubulin and promotes spindle assembly (1).

Reference
1. Jiang, H., Wang, S., Huang, Y., He, X., Cui, H., Zhu, X., & Zheng, Y. (2015) Phase transition of spindle-associated protein regulate spindle apparatus assembly. Cell, 163(1), 108-122. PMID: 26388440


There are 37 genes.  Reviewed (0 or Unreviewed (37

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Poa-0200
ENSPPYG00000000411.2
H2N4D6
2
LLPS-Poa-1170
ENSPPYG00000017288.2
H2PL98
3
LLPS-Poa-2423
ENSPPYG00000012139.2
H2P5C5
4
LLPS-Poa-2874
ENSPPYG00000014539.2
H2PCQ4
5
LLPS-Poa-0098
ENSPPYG00000011148.2
A0A2J8TXS8
AURKA
6
LLPS-Poa-1032
ENSPPYG00000007953.2
H2NSM9
AURKB
7
LLPS-Poa-2036
ENSPPYG00000008464.2
A0A2J8WAB5
CDC6
8
LLPS-Poa-0896
ENSPPYG00000005537.1
H2NKF3
CHAMP1
9
LLPS-Poa-4390
ENSPPYG00000005390.2
H2NJZ2
CKAP2
10
LLPS-Poa-0379
ENSPPYG00000003316.2
H2NDK2
CKAP5
11
LLPS-Poa-3811
ENSPPYG00000016072.2
H2PHG3
CLTB
12
LLPS-Poa-2490
ENSPPYG00000020013.2
H2PUL4
DCTN3
13
LLPS-Poa-1749
ENSPPYG00000005838.1
H2NLB1
DLGAP5
14
LLPS-Poa-3353
ENSPPYG00000018458.1
Q5R9Y6
DPYSL2
15
LLPS-Poa-2664
ENSPPYG00000006786.2
A0A2J8VXG9
FES
16
LLPS-Poa-0436
ENSPPYG00000001087.2
H2N6J7
GPSM2
17
LLPS-Poa-2349
ENSPPYG00000010733.2
H2P140
KAT14
18
LLPS-Poa-0868
ENSPPYG00000005253.2
A0A2J8UTE1
KATNAL1
19
LLPS-Poa-2520
ENSPPYG00000002484.1
H2NB08
KIF11
20
LLPS-Poa-0178
ENSPPYG00000015029.2
H2PE76
MAD2L1
21
LLPS-Poa-0968
ENSPPYG00000001885.2
H2N940
MAD2L2
22
LLPS-Poa-0135
ENSPPYG00000010912.2
A0A0A0MXP9
MAPRE1
23
LLPS-Poa-0824
ENSPPYG00000001392.2
H2N7I7
MKNK1
24
LLPS-Poa-2762
ENSPPYG00000020419.2
H2PVV3
MSN
25
LLPS-Poa-3866
ENSPPYG00000018390.2
H2PPN2
MTUS1
26
LLPS-Poa-0822
ENSPPYG00000002262.1
A0A2J8R2Q2
NCOA4
27
LLPS-Poa-1678
ENSPPYG00000002197.2
H2NA55
PARD3
28
LLPS-Poa-0108
ENSPPYG00000006791.2
H2NP82
PRC1
29
LLPS-Poa-4295
ENSPPYG00000007468.2
H2NR89
RANBP10
30
LLPS-Poa-3184
ENSPPYG00000018487.2
H2PPZ4
RBPMS
31
LLPS-Poa-0286
ENSPPYG00000013353.1
Q5RA66
SEPT2
32
LLPS-Poa-0567
ENSPPYG00000002645.2
Q5R4K5
SMC3
33
LLPS-Poa-0428
ENSPPYG00000011828.2
A0A2J8UWP8
SUN2
34
LLPS-Poa-1790
ENSPPYG00000013679.2
A0A2J8WDR3
TADA3
35
LLPS-Poa-3366
ENSPPYG00000001911.2
H2N971
TMEM201
36
LLPS-Poa-0601
ENSPPYG00000007922.2
H2NSJ8
ZBTB4
37
LLPS-Poa-0006
ENSPPYG00000008161.2
H2NTA4
ZNF207