Pelodiscus sinensis      Spindle apparatus


※ Spindle apparatus introduction

    The spindle is an important structure when cells divide. Phase separation promotes the concentration of molecules into the droplets, thereby promoting biochemical reactions. Some protein mixtures undergo a phase change to form droplets that concentrate actin to promote F-actin assembly in vitro. In addition, studies have shown that the phase transition of spindle regulatory protein BuGZ concentrates tubulin and promotes MT polymerizationbinds to tubulin and promotes spindle assembly (1).

Reference
1. Jiang, H., Wang, S., Huang, Y., He, X., Cui, H., Zhu, X., & Zheng, Y. (2015) Phase transition of spindle-associated protein regulate spindle apparatus assembly. Cell, 163(1), 108-122. PMID: 26388440


There are 34 genes.  Reviewed (0 or Unreviewed (34

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Pes-0172
ENSPSIG00000007339.1
K7FJ74
2
LLPS-Pes-1021
ENSPSIG00000012720.1
K7G1N3
3
LLPS-Pes-1149
ENSPSIG00000003132.1
K7F5G5
4
LLPS-Pes-2248
ENSPSIG00000014597.1
K7G7X3
5
LLPS-Pes-2394
ENSPSIG00000005969.1
K7FEP9
6
LLPS-Pes-3598
ENSPSIG00000005910.1
K7FEC4
7
LLPS-Pes-3707
ENSPSIG00000017322.1
K7GGX0
8
LLPS-Pes-2476
ENSPSIG00000002363.1
K7F2Y2
CDC6
9
LLPS-Pes-1823
ENSPSIG00000008434.1
K7FMK9
CHAMP1
10
LLPS-Pes-0467
ENSPSIG00000003799.1
K7F7L4
CKAP2
11
LLPS-Pes-2055
ENSPSIG00000011041.1
K7FW16
DLGAP5
12
LLPS-Pes-2105
ENSPSIG00000016087.1
K7GD40
DPYSL2
13
LLPS-Pes-2378
ENSPSIG00000003551.1
K7F6T0
DYRK3
14
LLPS-Pes-3035
ENSPSIG00000016557.1
K7GEC5
HAUS3
15
LLPS-Pes-0358
ENSPSIG00000006752.1
K7FH09
KAT14
16
LLPS-Pes-1548
ENSPSIG00000017091.1
K7GG23
KATNA1
17
LLPS-Pes-0602
ENSPSIG00000014936.1
K7G9F9
KIF11
18
LLPS-Pes-0285
ENSPSIG00000013328.1
K7G3P0
MAD2L1
19
LLPS-Pes-3809
ENSPSIG00000005974.1
K7FEJ0
MAPK6
20
LLPS-Pes-2735
ENSPSIG00000014443.1
K7G7K9
MSN
21
LLPS-Pes-1251
ENSPSIG00000006751.1
K7FIV2
MTOR
22
LLPS-Pes-2824
ENSPSIG00000005369.1
K7FCM5
NCOA4
23
LLPS-Pes-1389
ENSPSIG00000011834.1
K7FZQ0
PARD3
24
LLPS-Pes-2383
ENSPSIG00000007615.1
K7FK66
RANBP10
25
LLPS-Pes-1958
ENSPSIG00000006136.1
K7FF84
RBPMS
26
LLPS-Pes-0940
ENSPSIG00000009642.1
K7FRR1
SEPT2
27
LLPS-Pes-2313
ENSPSIG00000010608.1
K7FVS7
SMC3
28
LLPS-Pes-1051
ENSPSIG00000004554.1
K7FA13
SUN1
29
LLPS-Pes-2223
ENSPSIG00000004323.1
K7F9C1
SUN2
30
LLPS-Pes-3133
ENSPSIG00000002777.1
K7F497
TADA3
31
LLPS-Pes-0811
ENSPSIG00000012544.1
K7G120
TPR
32
LLPS-Pes-2405
ENSPSIG00000003437.1
K7F6F2
TPX2
33
LLPS-Pes-2286
ENSPSIG00000001270.1
K7EZQ7
ZBTB4
34
LLPS-Pes-1281
ENSPSIG00000017296.1
K7GGS3
ZNF207