Pan paniscus      Spindle apparatus


※ Spindle apparatus introduction

    The spindle is an important structure when cells divide. Phase separation promotes the concentration of molecules into the droplets, thereby promoting biochemical reactions. Some protein mixtures undergo a phase change to form droplets that concentrate actin to promote F-actin assembly in vitro. In addition, studies have shown that the phase transition of spindle regulatory protein BuGZ concentrates tubulin and promotes MT polymerizationbinds to tubulin and promotes spindle assembly (1).

Reference
1. Jiang, H., Wang, S., Huang, Y., He, X., Cui, H., Zhu, X., & Zheng, Y. (2015) Phase transition of spindle-associated protein regulate spindle apparatus assembly. Cell, 163(1), 108-122. PMID: 26388440


There are 41 genes.  Reviewed (0 or Unreviewed (41

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Pap-2552
ENSPPAG00000019218.1
A0A2R8ZL14
2
LLPS-Pap-3660
ENSPPAG00000038125.1
A0A2R9BUN0
3
LLPS-Pap-3953
ENSPPAG00000027623.1
A0A2R8ZUX4
4
LLPS-Pap-4268
ENSPPAG00000028808.1
A0A2R9A2X4
5
LLPS-Pap-0394
ENSPPAG00000031434.1
A0A2R9ANX1
AURKA
6
LLPS-Pap-3695
ENSPPAG00000029312.1
A0A2R9A9Y3
AURKB
7
LLPS-Pap-2051
ENSPPAG00000038406.1
A0A2R9BWL4
CDC6
8
LLPS-Pap-3028
ENSPPAG00000012131.1
A0A2R8ZGJ9
CHAMP1
9
LLPS-Pap-3910
ENSPPAG00000034419.1
A0A2R9AZI9
CKAP2
10
LLPS-Pap-2804
ENSPPAG00000030676.1
A0A2R9AEI9
CKAP5
11
LLPS-Pap-2691
ENSPPAG00000025339.1
A0A2R8ZNS1
DCTN3
12
LLPS-Pap-2259
ENSPPAG00000027413.1
A0A2R8ZTX8
DLGAP5
13
LLPS-Pap-1881
ENSPPAG00000035831.1
A0A2R9B742
DPYSL2
14
LLPS-Pap-4155
ENSPPAG00000036822.1
A0A2R9BLG6
DYRK3
15
LLPS-Pap-3033
ENSPPAG00000035301.1
A0A2R9B814
FES
16
LLPS-Pap-3699
ENSPPAG00000032988.1
A0A2R9AQB4
HAUS3
17
LLPS-Pap-2788
ENSPPAG00000036089.1
A0A2R9BCD2
HAUS6
18
LLPS-Pap-4130
ENSPPAG00000026129.1
A0A2R8ZVZ4
KAT14
19
LLPS-Pap-2204
ENSPPAG00000033530.1
A0A2R9ATJ5
KATNAL1
20
LLPS-Pap-0192
ENSPPAG00000043128.1
A0A2R9CQJ9
KIF11
21
LLPS-Pap-0536
ENSPPAG00000028274.1
A0A2R8ZZQ3
MAD2L1
22
LLPS-Pap-3568
ENSPPAG00000035539.1
A0A2R9B5F6
MAD2L2
23
LLPS-Pap-1570
ENSPPAG00000026917.1
A0A2R8ZUR4
MAPK6
24
LLPS-Pap-2550
ENSPPAG00000025593.1
A0A2R8ZQE6
MAPRE1
25
LLPS-Pap-0611
ENSPPAG00000000987.1
A0A2R8Z6D9
MKNK1
26
LLPS-Pap-0414
ENSPPAG00000034551.1
A0A2R9AZK0
MSN
27
LLPS-Pap-4457
ENSPPAG00000036364.1
A0A2R9BI87
MTOR
28
LLPS-Pap-4402
ENSPPAG00000028269.1
A0A2R8ZYS5
NCOA4
29
LLPS-Pap-1767
ENSPPAG00000038592.1
A0A2R9BZ02
PARD3
30
LLPS-Pap-1440
ENSPPAG00000033888.1
A0A2R9AW17
PRC1
31
LLPS-Pap-3552
ENSPPAG00000038250.1
A0A2R9BQR8
RANBP10
32
LLPS-Pap-1659
ENSPPAG00000033108.1
A0A2R9AXR2
RBPMS
33
LLPS-Pap-2046
ENSPPAG00000034127.1
A0A2R9B1V4
SEPT2
34
LLPS-Pap-2666
ENSPPAG00000031039.1
A0A2R9AH80
SMC3
35
LLPS-Pap-2772
ENSPPAG00000041385.1
A0A2R9C606
SUN1
36
LLPS-Pap-1961
ENSPPAG00000038642.1
A0A2R9BP74
SUN2
37
LLPS-Pap-3409
ENSPPAG00000042708.1
A0A2R9CDX4
TADA3
38
LLPS-Pap-0961
ENSPPAG00000039995.1
A0A2R9C708
TMEM201
39
LLPS-Pap-0816
ENSPPAG00000040829.1
A0A2R9CDL4
TPR
40
LLPS-Pap-2622
ENSPPAG00000039063.1
A0A2R9BV67
ZBTB4
41
LLPS-Pap-1937
ENSPPAG00000032098.1
A0A2R9AR02
ZNF207