Ostreococcus lucimarinus      Spindle apparatus


※ Spindle apparatus introduction

    The spindle is an important structure when cells divide. Phase separation promotes the concentration of molecules into the droplets, thereby promoting biochemical reactions. Some protein mixtures undergo a phase change to form droplets that concentrate actin to promote F-actin assembly in vitro. In addition, studies have shown that the phase transition of spindle regulatory protein BuGZ concentrates tubulin and promotes MT polymerizationbinds to tubulin and promotes spindle assembly (1).

Reference
1. Jiang, H., Wang, S., Huang, Y., He, X., Cui, H., Zhu, X., & Zheng, Y. (2015) Phase transition of spindle-associated protein regulate spindle apparatus assembly. Cell, 163(1), 108-122. PMID: 26388440


There are 8 genes.  Reviewed (0 or Unreviewed (8

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Osl-1173
OSTLU_2293
A4RXV4
OSTLU_2293
2
LLPS-Osl-0050
OSTLU_24577
A4RXN9
OSTLU_24577
3
LLPS-Osl-0436
OSTLU_25198
A4S4C6
OSTLU_25198
4
LLPS-Osl-1160
OSTLU_37384
A4RVM7
OSTLU_37384
5
LLPS-Osl-0799
OSTLU_39040
A4S5J1
OSTLU_39040
6
LLPS-Osl-0312
OSTLU_43679
A4SB60
OSTLU_43679
7
LLPS-Osl-0287
OSTLU_46490
A4S2L6
OSTLU_46490
8
LLPS-Osl-0931
OSTLU_50090
A4RZK4
OSTLU_50090