Neurospora crassa      Spindle apparatus


※ Spindle apparatus introduction

    The spindle is an important structure when cells divide. Phase separation promotes the concentration of molecules into the droplets, thereby promoting biochemical reactions. Some protein mixtures undergo a phase change to form droplets that concentrate actin to promote F-actin assembly in vitro. In addition, studies have shown that the phase transition of spindle regulatory protein BuGZ concentrates tubulin and promotes MT polymerizationbinds to tubulin and promotes spindle assembly (1).

Reference
1. Jiang, H., Wang, S., Huang, Y., He, X., Cui, H., Zhu, X., & Zheng, Y. (2015) Phase transition of spindle-associated protein regulate spindle apparatus assembly. Cell, 163(1), 108-122. PMID: 26388440


There are 13 genes.  Reviewed (0 or Unreviewed (13

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Nec-1285
NCU06577
Q1K8E6
mus-26
2
LLPS-Nec-1008
NCU00927
Q7SFC0
NCU00927
3
LLPS-Nec-0186
NCU01409
Q7S7G6
NCU01409
4
LLPS-Nec-1085
NCU02776
Q7SE18
NCU02776
5
LLPS-Nec-0042
NCU03207
Q7SGW2
NCU03207
6
LLPS-Nec-0849
NCU04059
Q7RZF8
NCU04059
7
LLPS-Nec-0567
NCU04535
Q7RY29
NCU04535
8
LLPS-Nec-0318
NCU05781
Q7S5R2
NCU05781
9
LLPS-Nec-0989
NCU06145
Q7S5E3
NCU06145
10
LLPS-Nec-1120
NCU06277
Q7SB64
NCU06277
11
LLPS-Nec-0198
NCU07554
Q7S024
NCU07554
12
LLPS-Nec-0236
NCU00108
Q7RYM0
stk-13
13
LLPS-Nec-0642
NCU03954
P53377
tbg