Neosartorya fischeri      Spindle apparatus


※ Spindle apparatus introduction

    The spindle is an important structure when cells divide. Phase separation promotes the concentration of molecules into the droplets, thereby promoting biochemical reactions. Some protein mixtures undergo a phase change to form droplets that concentrate actin to promote F-actin assembly in vitro. In addition, studies have shown that the phase transition of spindle regulatory protein BuGZ concentrates tubulin and promotes MT polymerizationbinds to tubulin and promotes spindle assembly (1).

Reference
1. Jiang, H., Wang, S., Huang, Y., He, X., Cui, H., Zhu, X., & Zheng, Y. (2015) Phase transition of spindle-associated protein regulate spindle apparatus assembly. Cell, 163(1), 108-122. PMID: 26388440


There are 11 genes.  Reviewed (0 or Unreviewed (11

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Nef-1143
NFIA_020150
A1D4G4
NFIA_020150
2
LLPS-Nef-1142
NFIA_020960
A1D4P5
NFIA_020960
3
LLPS-Nef-1638
NFIA_025280
A1DC96
NFIA_025280
4
LLPS-Nef-0428
NFIA_058920
A1DP20
NFIA_058920
5
LLPS-Nef-0586
NFIA_059040
A1DP32
NFIA_059040
6
LLPS-Nef-0051
NFIA_062960
A1D5Z1
NFIA_062960
7
LLPS-Nef-0820
NFIA_089270
A1DHW3
NFIA_089270
8
LLPS-Nef-0768
NFIA_091130
A1DIE7
NFIA_091130
9
LLPS-Nef-0062
NFIA_091520
A1DII6
NFIA_091520
10
LLPS-Nef-0577
NFIA_114090
A1D917
NFIA_114090
11
LLPS-Nef-1265
NFIA_114840
A1D990
NFIA_114840