Myotis lucifugus      Spindle apparatus


※ Spindle apparatus introduction

    The spindle is an important structure when cells divide. Phase separation promotes the concentration of molecules into the droplets, thereby promoting biochemical reactions. Some protein mixtures undergo a phase change to form droplets that concentrate actin to promote F-actin assembly in vitro. In addition, studies have shown that the phase transition of spindle regulatory protein BuGZ concentrates tubulin and promotes MT polymerizationbinds to tubulin and promotes spindle assembly (1).

Reference
1. Jiang, H., Wang, S., Huang, Y., He, X., Cui, H., Zhu, X., & Zheng, Y. (2015) Phase transition of spindle-associated protein regulate spindle apparatus assembly. Cell, 163(1), 108-122. PMID: 26388440


There are 38 genes.  Reviewed (0 or Unreviewed (38

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Myl-0224
ENSMLUG00000029589.1
G1Q4Q7
2
LLPS-Myl-0721
ENSMLUG00000026895.1
G1Q7N6
3
LLPS-Myl-2416
ENSMLUG00000000132.2
G1NSK8
4
LLPS-Myl-2835
ENSMLUG00000004295.2
G1P265
5
LLPS-Myl-3372
ENSMLUG00000013841.2
G1PNR6
6
LLPS-Myl-3960
ENSMLUG00000016085.2
G1PTT8
7
LLPS-Myl-1799
ENSMLUG00000007925.2
G1PAC6
AURKA
8
LLPS-Myl-0665
ENSMLUG00000007587.2
G1P9K6
AURKC
9
LLPS-Myl-1809
ENSMLUG00000010600.2
G1PGA7
CDC6
10
LLPS-Myl-2150
ENSMLUG00000011032.2
G1PH89
CHAMP1
11
LLPS-Myl-1082
ENSMLUG00000017633.2
G1PXB7
CKAP5
12
LLPS-Myl-0009
ENSMLUG00000001994.2
G1NWU1
DCTN3
13
LLPS-Myl-2210
ENSMLUG00000010429.2
G1PFY7
DLGAP5
14
LLPS-Myl-2755
ENSMLUG00000000271.2
G1NSX4
DPYSL2
15
LLPS-Myl-0407
ENSMLUG00000001418.2
G1NVJ5
DYRK3
16
LLPS-Myl-3374
ENSMLUG00000010532.2
G1PG58
GPSM2
17
LLPS-Myl-1802
ENSMLUG00000028862.1
G1Q134
HAUS3
18
LLPS-Myl-3357
ENSMLUG00000010873.2
G1PGZ1
HAUS6
19
LLPS-Myl-0615
ENSMLUG00000007259.2
G1P8W7
KAT14
20
LLPS-Myl-3710
ENSMLUG00000006028.2
G1P636
KATNAL1
21
LLPS-Myl-0266
ENSMLUG00000013323.2
G1PMJ6
KIF11
22
LLPS-Myl-2232
ENSMLUG00000006852.2
G1P7Z1
MAD2L2
23
LLPS-Myl-0110
ENSMLUG00000000823.2
G1NU67
MAPK6
24
LLPS-Myl-2218
ENSMLUG00000016403.2
G1PUI6
MAPRE1
25
LLPS-Myl-1681
ENSMLUG00000007816.2
G1PA45
MKNK1
26
LLPS-Myl-4183
ENSMLUG00000007850.2
G1PA90
MTUS1
27
LLPS-Myl-3536
ENSMLUG00000000619.2
G1NTQ2
NCOA4
28
LLPS-Myl-0492
ENSMLUG00000005821.2
G1P5M9
RANBP10
29
LLPS-Myl-0055
ENSMLUG00000013394.2
G1PMQ3
RBPMS2
30
LLPS-Myl-0405
ENSMLUG00000011922.2
G1PJE2
RDX
31
LLPS-Myl-0073
ENSMLUG00000007108.2
G1P8I5
SEPT2
32
LLPS-Myl-1369
ENSMLUG00000013777.2
G1PNL6
SMC3
33
LLPS-Myl-1522
ENSMLUG00000002094.2
G1NX26
SUN1
34
LLPS-Myl-0695
ENSMLUG00000003774.2
G1P0Y4
SUN2
35
LLPS-Myl-1382
ENSMLUG00000012978.2
G1PLR3
TADA3
36
LLPS-Myl-3785
ENSMLUG00000011841.2
G1PJ69
TMEM201
37
LLPS-Myl-0983
ENSMLUG00000016913.2
G1PVP4
TPR
38
LLPS-Myl-1252
ENSMLUG00000009961.2
G1PEW3
ZBTB4