Mustela putorius furo      Spindle apparatus


※ Spindle apparatus introduction

    The spindle is an important structure when cells divide. Phase separation promotes the concentration of molecules into the droplets, thereby promoting biochemical reactions. Some protein mixtures undergo a phase change to form droplets that concentrate actin to promote F-actin assembly in vitro. In addition, studies have shown that the phase transition of spindle regulatory protein BuGZ concentrates tubulin and promotes MT polymerizationbinds to tubulin and promotes spindle assembly (1).

Reference
1. Jiang, H., Wang, S., Huang, Y., He, X., Cui, H., Zhu, X., & Zheng, Y. (2015) Phase transition of spindle-associated protein regulate spindle apparatus assembly. Cell, 163(1), 108-122. PMID: 26388440


There are 39 genes.  Reviewed (0 or Unreviewed (39

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Mup-2233
ENSMPUG00000006397.1
M3Y4U0
AURKC
2
LLPS-Mup-0751
ENSMPUG00000014897.1
M3YTX6
CDC6
3
LLPS-Mup-2933
ENSMPUG00000018670.1
M3Z4N9
CHAMP1
4
LLPS-Mup-4299
ENSMPUG00000017996.1
M3Z2S3
CKAP2
5
LLPS-Mup-2662
ENSMPUG00000005279.1
M3Y1P0
CKAP5
6
LLPS-Mup-1945
ENSMPUG00000012543.1
M3YM91
CLTB
7
LLPS-Mup-0081
ENSMPUG00000004267.1
M3XYT1
DCTN3
8
LLPS-Mup-2420
ENSMPUG00000005767.1
M3Y319
DLGAP5
9
LLPS-Mup-3485
ENSMPUG00000000862.1
M3XP58
DPYSL2
10
LLPS-Mup-0847
ENSMPUG00000010083.1
M3YFA1
DYRK3
11
LLPS-Mup-0431
ENSMPUG00000015662.1
M3YW42
FES
12
LLPS-Mup-2760
ENSMPUG00000002764.1
M3XUI6
GPSM2
13
LLPS-Mup-3320
ENSMPUG00000011011.1
M3YHW5
HAUS3
14
LLPS-Mup-2201
ENSMPUG00000010535.1
M3YGK0
HAUS6
15
LLPS-Mup-1756
ENSMPUG00000001292.1
M3XQD1
KAT14
16
LLPS-Mup-2988
ENSMPUG00000004610.1
M3XZS4
KATNAL1
17
LLPS-Mup-1407
ENSMPUG00000017220.1
M3Z0K0
KIF11
18
LLPS-Mup-0118
ENSMPUG00000017416.1
M3Z144
MAD2L1
19
LLPS-Mup-0077
ENSMPUG00000016422.1
M3YYA8
MAD2L2
20
LLPS-Mup-4488
ENSMPUG00000007628.1
M3Y8B6
MAPK6
21
LLPS-Mup-0175
ENSMPUG00000017867.1
M3Z2E4
MAPRE1
22
LLPS-Mup-3306
ENSMPUG00000012773.1
M3YMX1
MKNK1
23
LLPS-Mup-1744
ENSMPUG00000001169.1
M3XQ08
MSN
24
LLPS-Mup-1870
ENSMPUG00000016429.1
M3YYB5
MTOR
25
LLPS-Mup-4545
ENSMPUG00000017966.1
M3Z2P3
MTUS1
26
LLPS-Mup-1406
ENSMPUG00000004661.1
M3XZX3
MTUS2
27
LLPS-Mup-1910
ENSMPUG00000009483.1
M3YDK0
NCOA4
28
LLPS-Mup-2101
ENSMPUG00000005938.1
M3Y3I7
PARD3
29
LLPS-Mup-4540
ENSMPUG00000006547.1
M3Y590
RANBP10
30
LLPS-Mup-3696
ENSMPUG00000011314.1
M3YIR5
RBPMS
31
LLPS-Mup-1003
ENSMPUG00000000166.1
M3XM63
SEPT2
32
LLPS-Mup-0866
ENSMPUG00000002074.1
M3XSK3
SMC3
33
LLPS-Mup-1691
ENSMPUG00000017885.1
M3Z2G3
SUN1
34
LLPS-Mup-1006
ENSMPUG00000013182.1
M3YP27
SUN2
35
LLPS-Mup-0774
ENSMPUG00000017125.1
M3Z0A5
TADA3
36
LLPS-Mup-1122
ENSMPUG00000006268.1
M3Y4G3
TMEM201
37
LLPS-Mup-1959
ENSMPUG00000012051.1
M3YKV2
TPR
38
LLPS-Mup-4457
ENSMPUG00000009666.1
M3YE33
ZBTB4
39
LLPS-Mup-0364
ENSMPUG00000014761.1
M3YTJ2
ZNF207