※ Spindle apparatus introduction

    The spindle is an important structure when cells divide. Phase separation promotes the concentration of molecules into the droplets, thereby promoting biochemical reactions. Some protein mixtures undergo a phase change to form droplets that concentrate actin to promote F-actin assembly in vitro. In addition, studies have shown that the phase transition of spindle regulatory protein BuGZ concentrates tubulin and promotes MT polymerizationbinds to tubulin and promotes spindle assembly (1).

Reference
1. Jiang, H., Wang, S., Huang, Y., He, X., Cui, H., Zhu, X., & Zheng, Y. (2015) Phase transition of spindle-associated protein regulate spindle apparatus assembly. Cell, 163(1), 108-122. PMID: 26388440

  Reviewed (0)  or Unreviewed (40) 

No.	Status	DrLLPS ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		LLPS-Mod-0214	ENSMODG00000023883.1	F7A843
2		LLPS-Mod-0972	ENSMODG00000010436.3	F6YT21
3		LLPS-Mod-1391	ENSMODG00000014675.3	F7E7N5
4		LLPS-Mod-2424	ENSMODG00000006962.4	F6QVE7
5		LLPS-Mod-3377	ENSMODG00000013986.3	F6QKZ1
6		LLPS-Mod-3801	ENSMODG00000019046.3	F7DKL8
7		LLPS-Mod-0263	ENSMODG00000016435.3	F7ASA8	AURKA
8		LLPS-Mod-2641	ENSMODG00000013108.3	F7BMZ5	CDC6
9		LLPS-Mod-0618	ENSMODG00000003128.3	F6WV14	CHAMP1
10		LLPS-Mod-0761	ENSMODG00000019897.3	F6W5T2	CKAP5
11		LLPS-Mod-4243	ENSMODG00000005190.3	F7DN20	CLTB
12		LLPS-Mod-0656	ENSMODG00000007953.2	F7G8T6	DCTN3
13		LLPS-Mod-2635	ENSMODG00000016680.2	F7DMI7	DPYSL2
14		LLPS-Mod-1015	ENSMODG00000019456.1	F6RWR2	FES
15		LLPS-Mod-2858	ENSMODG00000002268.3	F7CVY1	GPSM2
16		LLPS-Mod-1759	ENSMODG00000004050.3	F7C3W0	HAUS3
17		LLPS-Mod-4098	ENSMODG00000005543.2	F7FHH1	KAT14
18		LLPS-Mod-2148	ENSMODG00000009220.3	F7EEC8	KATNAL1
19		LLPS-Mod-0011	ENSMODG00000006467.3	F7FGI6	KIF11
20		LLPS-Mod-1213	ENSMODG00000018944.3	F7GB10	MAD2L1
21		LLPS-Mod-2910	ENSMODG00000011006.3	F7A0K3	MAD2L2
22		LLPS-Mod-2896	ENSMODG00000001962.2	F6V2H6	MAPK6
23		LLPS-Mod-0053	ENSMODG00000019445.3	F6RY10	MAPRE1
24		LLPS-Mod-3528	ENSMODG00000015753.2	F7AH31	MAPRE3
25		LLPS-Mod-1491	ENSMODG00000003911.2	F7CNW2	MARVELD1
26		LLPS-Mod-1121	ENSMODG00000001951.3	F6VJP3	MKNK1
27		LLPS-Mod-0540	ENSMODG00000012494.3	F7D1B8	MSN
28		LLPS-Mod-3922	ENSMODG00000011138.3	F7BA89	MTOR
29		LLPS-Mod-2118	ENSMODG00000002682.3	F7CYN9	NCOA4
30		LLPS-Mod-0925	ENSMODG00000007069.3	F6UEX0	PARD3
31		LLPS-Mod-2747	ENSMODG00000005615.3	F7CZC7	RANBP10
32		LLPS-Mod-1968	ENSMODG00000019006.2	F7CP63	RBPMS
33		LLPS-Mod-0375	ENSMODG00000016041.3	F6YUL8	SEPT2
34		LLPS-Mod-1611	ENSMODG00000010463.3	F7BL05	SMC3
35		LLPS-Mod-1766	ENSMODG00000008621.3	F6TCF6	SUN1
36		LLPS-Mod-2208	ENSMODG00000009597.3	F6RQM4	SUN2
37		LLPS-Mod-0851	ENSMODG00000005129.2	F7EQN3	TADA3
38		LLPS-Mod-0713	ENSMODG00000003031.3	F6Q1V4	TMEM201
39		LLPS-Mod-0627	ENSMODG00000011641.3	F6TJ68	TPR
40		LLPS-Mod-0501	ENSMODG00000019185.3	F7AWJ6	ZNF207