Microbotryum violaceum      Spindle apparatus


※ Spindle apparatus introduction

    The spindle is an important structure when cells divide. Phase separation promotes the concentration of molecules into the droplets, thereby promoting biochemical reactions. Some protein mixtures undergo a phase change to form droplets that concentrate actin to promote F-actin assembly in vitro. In addition, studies have shown that the phase transition of spindle regulatory protein BuGZ concentrates tubulin and promotes MT polymerizationbinds to tubulin and promotes spindle assembly (1).

Reference
1. Jiang, H., Wang, S., Huang, Y., He, X., Cui, H., Zhu, X., & Zheng, Y. (2015) Phase transition of spindle-associated protein regulate spindle apparatus assembly. Cell, 163(1), 108-122. PMID: 26388440


There are 9 genes.  Reviewed (0 or Unreviewed (9

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Miv-1406
MVLG_01914
U5H3K2
MVLG_01914
2
LLPS-Miv-0254
MVLG_01960
U5H3P9
MVLG_01960
3
LLPS-Miv-0026
MVLG_02664
U5H5V5
MVLG_02664
4
LLPS-Miv-0528
MVLG_02753
U5H649
MVLG_02753
5
LLPS-Miv-1136
MVLG_03329
U5H7V9
MVLG_03329
6
LLPS-Miv-0370
MVLG_05462
U5HEB7
MVLG_05462
7
LLPS-Miv-0347
MVLG_06112
U5HGA0
MVLG_06112
8
LLPS-Miv-0215
MVLG_06440
U5HHA4
MVLG_06440
9
LLPS-Miv-0907
MVLG_07019
U5HJ25
MVLG_07019