Meleagris gallopavo      Spindle apparatus


※ Spindle apparatus introduction

    The spindle is an important structure when cells divide. Phase separation promotes the concentration of molecules into the droplets, thereby promoting biochemical reactions. Some protein mixtures undergo a phase change to form droplets that concentrate actin to promote F-actin assembly in vitro. In addition, studies have shown that the phase transition of spindle regulatory protein BuGZ concentrates tubulin and promotes MT polymerizationbinds to tubulin and promotes spindle assembly (1).

Reference
1. Jiang, H., Wang, S., Huang, Y., He, X., Cui, H., Zhu, X., & Zheng, Y. (2015) Phase transition of spindle-associated protein regulate spindle apparatus assembly. Cell, 163(1), 108-122. PMID: 26388440


There are 30 genes.  Reviewed (0 or Unreviewed (30

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Meg-0930
ENSMGAG00000010722.2
G1NE31
2
LLPS-Meg-1171
ENSMGAG00000011604.1
G1NGE1
3
LLPS-Meg-2155
ENSMGAG00000011538.1
G1NG95
4
LLPS-Meg-2252
ENSMGAG00000003989.1
G1MXY7
5
LLPS-Meg-3037
ENSMGAG00000015036.2
G3UPL0
6
LLPS-Meg-0351
ENSMGAG00000014836.1
G1NPQ4
CHAMP1
7
LLPS-Meg-0570
ENSMGAG00000010880.2
G1NEK8
CKAP5
8
LLPS-Meg-1026
ENSMGAG00000007069.2
G1N5D4
CLTA
9
LLPS-Meg-0864
ENSMGAG00000017118.1
G3UV58
DCTN3
10
LLPS-Meg-1109
ENSMGAG00000013648.1
G1NLM0
DLGAP5
11
LLPS-Meg-1869
ENSMGAG00000000749.2
G1MQ15
DPYSL2
12
LLPS-Meg-0730
ENSMGAG00000003702.2
G1MX88
DYRK3
13
LLPS-Meg-2973
ENSMGAG00000006084.1
G1N329
GPSM2
14
LLPS-Meg-2192
ENSMGAG00000013033.1
G1NK34
HAUS3
15
LLPS-Meg-2371
ENSMGAG00000006755.2
G1N4M4
KAT14
16
LLPS-Meg-0849
ENSMGAG00000012608.1
G1NJ12
KATNA1
17
LLPS-Meg-0040
ENSMGAG00000009062.1
G1NA61
KIF11
18
LLPS-Meg-0451
ENSMGAG00000010720.1
G1NE25
MAD2L1
19
LLPS-Meg-2386
ENSMGAG00000006335.1
G1N3N6
MAD2L2
20
LLPS-Meg-1173
ENSMGAG00000007478.2
G5E7Q6
MAPRE1
21
LLPS-Meg-2704
ENSMGAG00000000771.2
G1MQ39
MSN
22
LLPS-Meg-2132
ENSMGAG00000004758.2
G1MZX7
MTOR
23
LLPS-Meg-1214
ENSMGAG00000002354.2
G1MTZ3
NCOA4
24
LLPS-Meg-2349
ENSMGAG00000005916.2
G1N2S3
PARD3
25
LLPS-Meg-2322
ENSMGAG00000002787.2
G1MV01
RANBP10
26
LLPS-Meg-1506
ENSMGAG00000005088.1
G1N0K6
RBPMS
27
LLPS-Meg-1421
ENSMGAG00000003759.1
G1MXE2
SEPT2
28
LLPS-Meg-1114
ENSMGAG00000008391.2
G1N8G9
TADA3
29
LLPS-Meg-0927
ENSMGAG00000001013.2
G1MQY3
TPR
30
LLPS-Meg-1247
ENSMGAG00000007868.1
G1N794
ZNF207