Mandrillus leucophaeus      Spindle apparatus


※ Spindle apparatus introduction

    The spindle is an important structure when cells divide. Phase separation promotes the concentration of molecules into the droplets, thereby promoting biochemical reactions. Some protein mixtures undergo a phase change to form droplets that concentrate actin to promote F-actin assembly in vitro. In addition, studies have shown that the phase transition of spindle regulatory protein BuGZ concentrates tubulin and promotes MT polymerizationbinds to tubulin and promotes spindle assembly (1).

Reference
1. Jiang, H., Wang, S., Huang, Y., He, X., Cui, H., Zhu, X., & Zheng, Y. (2015) Phase transition of spindle-associated protein regulate spindle apparatus assembly. Cell, 163(1), 108-122. PMID: 26388440


There are 38 genes.  Reviewed (0 or Unreviewed (38

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Mal-0254
ENSMLEG00000003588.1
A0A2K5XCD6
AURKA
2
LLPS-Mal-2091
ENSMLEG00000039429.1
A0A2K5ZRQ2
AURKB
3
LLPS-Mal-1523
ENSMLEG00000017384.1
A0A2K5XKU3
CDC6
4
LLPS-Mal-0645
ENSMLEG00000027271.1
A0A2K5XTY3
CHAMP1
5
LLPS-Mal-3710
ENSMLEG00000043706.1
A0A2K6AH36
CKAP2
6
LLPS-Mal-0428
ENSMLEG00000034738.1
A0A2K5Z0R2
CKAP5
7
LLPS-Mal-4572
ENSMLEG00000042205.1
A0A2K6A7Y4
CLTB
8
LLPS-Mal-2369
ENSMLEG00000043099.1
A0A2K6ADD2
DCTN3
9
LLPS-Mal-0720
ENSMLEG00000028124.1
A0A2K5XXI8
DLGAP5
10
LLPS-Mal-4044
ENSMLEG00000042022.1
A0A2K6A6T5
DPYSL2
11
LLPS-Mal-1291
ENSMLEG00000035913.1
A0A2K5Z6I2
DYRK3
12
LLPS-Mal-0149
ENSMLEG00000028597.1
A0A2K5Y0H5
FES
13
LLPS-Mal-2602
ENSMLEG00000037132.1
A0A2K5ZDN7
GPSM2
14
LLPS-Mal-2950
ENSMLEG00000035756.1
A0A2K5Z5J2
HAUS3
15
LLPS-Mal-1032
ENSMLEG00000041696.1
A0A2K6A521
KAT14
16
LLPS-Mal-2328
ENSMLEG00000029470.1
A0A2K5Y4S1
KATNA1
17
LLPS-Mal-1004
ENSMLEG00000040992.1
A0A2K6A0X6
KIF11
18
LLPS-Mal-0216
ENSMLEG00000036707.1
A0A2K5ZB55
MAD2L1
19
LLPS-Mal-1659
ENSMLEG00000029133.1
A0A2K5Y304
MAD2L2
20
LLPS-Mal-4598
ENSMLEG00000029288.1
A0A2K5Y3X1
MAPK6
21
LLPS-Mal-2171
ENSMLEG00000025038.1
A0A2K5XR73
MAPRE1
22
LLPS-Mal-0837
ENSMLEG00000043277.1
A0A2K6AEI3
MKNK1
23
LLPS-Mal-2944
ENSMLEG00000036805.1
A0A2K5ZCI2
MSN
24
LLPS-Mal-0361
ENSMLEG00000023675.1
A0A2K5XPX8
MTOR
25
LLPS-Mal-3607
ENSMLEG00000031629.1
A0A2K5YHK0
MTUS1
26
LLPS-Mal-4580
ENSMLEG00000028371.1
A0A2K5XYJ0
NCOA4
27
LLPS-Mal-1920
ENSMLEG00000031270.1
A0A2K5YGE2
PARD3B
28
LLPS-Mal-2915
ENSMLEG00000029927.1
A0A2K5Y883
RANBP10
29
LLPS-Mal-4331
ENSMLEG00000015635.1
A0A2K5XJY4
RBPMS
30
LLPS-Mal-1566
ENSMLEG00000043469.1
A0A2K6AFR3
SEPT2
31
LLPS-Mal-0984
ENSMLEG00000043852.1
A0A2K6AI75
SMC3
32
LLPS-Mal-0813
ENSMLEG00000031714.1
A0A2K5YIR0
SUN1
33
LLPS-Mal-0913
ENSMLEG00000032997.1
A0A2K5YQ22
SUN2
34
LLPS-Mal-2608
ENSMLEG00000037586.1
A0A2K5ZGP1
TADA3
35
LLPS-Mal-2719
ENSMLEG00000034051.1
A0A2K5YVV7
TMEM201
36
LLPS-Mal-0999
ENSMLEG00000037413.1
A0A2K5ZGL4
TPR
37
LLPS-Mal-1686
ENSMLEG00000028905.1
A0A2K5Y1P1
ZBTB4
38
LLPS-Mal-1870
ENSMLEG00000018149.1
A0A2K5XLB3
ZNF207