Macaca nemestrina      Spindle apparatus


※ Spindle apparatus introduction

    The spindle is an important structure when cells divide. Phase separation promotes the concentration of molecules into the droplets, thereby promoting biochemical reactions. Some protein mixtures undergo a phase change to form droplets that concentrate actin to promote F-actin assembly in vitro. In addition, studies have shown that the phase transition of spindle regulatory protein BuGZ concentrates tubulin and promotes MT polymerizationbinds to tubulin and promotes spindle assembly (1).

Reference
1. Jiang, H., Wang, S., Huang, Y., He, X., Cui, H., Zhu, X., & Zheng, Y. (2015) Phase transition of spindle-associated protein regulate spindle apparatus assembly. Cell, 163(1), 108-122. PMID: 26388440


There are 39 genes.  Reviewed (0 or Unreviewed (39

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Man-0266
ENSMNEG00000020907.1
A0A2K6AZG6
AURKA
2
LLPS-Man-0036
ENSMNEG00000028418.1
A0A2K6B8G2
AURKB
3
LLPS-Man-3379
ENSMNEG00000013211.1
A0A2K6AUK4
CDC6
4
LLPS-Man-2471
ENSMNEG00000033831.1
A0A2K6C8K6
CHAMP1
5
LLPS-Man-1853
ENSMNEG00000045159.1
A0A2K6EAQ4
CKAP2
6
LLPS-Man-0565
ENSMNEG00000045449.1
A0A2K6ECT4
CKAP5
7
LLPS-Man-0857
ENSMNEG00000040074.1
A0A2K6DCM1
CLTB
8
LLPS-Man-3743
ENSMNEG00000045508.1
A0A2K6ED53
DCTN3
9
LLPS-Man-1801
ENSMNEG00000043865.1
A0A2K6E237
DLGAP5
10
LLPS-Man-1139
ENSMNEG00000031797.1
A0A2K6BVH4
DPYSL2
11
LLPS-Man-4554
ENSMNEG00000043248.1
A0A2K6DXX3
DYRK3
12
LLPS-Man-1310
ENSMNEG00000042107.1
A0A2K6DRP0
FES
13
LLPS-Man-4471
ENSMNEG00000041492.1
A0A2K6DLP6
GPSM2
14
LLPS-Man-3661
ENSMNEG00000031199.1
A0A2K6BRI4
HAUS3
15
LLPS-Man-1527
ENSMNEG00000032919.1
A0A2K6C2R0
KAT14
16
LLPS-Man-4498
ENSMNEG00000036195.1
A0A2K6CP13
KATNAL1
17
LLPS-Man-0724
ENSMNEG00000020591.1
A0A2K6AZ70
KIF11
18
LLPS-Man-0625
ENSMNEG00000040691.1
A0A2K6DGQ4
MAD2L1
19
LLPS-Man-1731
ENSMNEG00000033726.1
A0A2K6C801
MAD2L2
20
LLPS-Man-2834
ENSMNEG00000036532.1
A0A2K6CR78
MAPK6
21
LLPS-Man-0011
ENSMNEG00000039307.1
A0A2K6D7M2
MAPRE1
22
LLPS-Man-2873
ENSMNEG00000009162.1
A0A2K6AS92
MARVELD1
23
LLPS-Man-0450
ENSMNEG00000037534.1
A0A2K6CX81
MKNK1
24
LLPS-Man-3967
ENSMNEG00000041403.1
A0A2K6DL37
MSN
25
LLPS-Man-3757
ENSMNEG00000029166.1
A0A2K6BF26
MTOR
26
LLPS-Man-3409
ENSMNEG00000032347.1
A0A2K6BZ90
MTUS1
27
LLPS-Man-3346
ENSMNEG00000040918.1
A0A2K6DHX5
NCOA4
28
LLPS-Man-0687
ENSMNEG00000034031.1
A0A2K6CE56
PARD3
29
LLPS-Man-3125
ENSMNEG00000033620.1
A0A2K6C7W1
RANBP10
30
LLPS-Man-1045
ENSMNEG00000043805.1
A0A2K6E1J3
RBPMS
31
LLPS-Man-1848
ENSMNEG00000004313.1
A0A2K6APA8
SEPT2
32
LLPS-Man-1654
ENSMNEG00000001042.1
A0A2K6AMW8
SMC3
33
LLPS-Man-0423
ENSMNEG00000038196.1
A0A2K6D0U5
SUN1
34
LLPS-Man-0505
ENSMNEG00000016085.1
A0A2K6AWC8
SUN2
35
LLPS-Man-1524
ENSMNEG00000034551.1
A0A2K6CDE0
TADA3
36
LLPS-Man-0338
ENSMNEG00000007380.1
A0A2K6AR77
TMEM201
37
LLPS-Man-1131
ENSMNEG00000034288.1
A0A2K6CCL3
TPR
38
LLPS-Man-2188
ENSMNEG00000017704.1
A0A2K6AX97
ZBTB4
39
LLPS-Man-3890
ENSMNEG00000041308.1
A0A2K6DKZ2
ZNF207