Latimeria chalumnae      Spindle apparatus


※ Spindle apparatus introduction

    The spindle is an important structure when cells divide. Phase separation promotes the concentration of molecules into the droplets, thereby promoting biochemical reactions. Some protein mixtures undergo a phase change to form droplets that concentrate actin to promote F-actin assembly in vitro. In addition, studies have shown that the phase transition of spindle regulatory protein BuGZ concentrates tubulin and promotes MT polymerizationbinds to tubulin and promotes spindle assembly (1).

Reference
1. Jiang, H., Wang, S., Huang, Y., He, X., Cui, H., Zhu, X., & Zheng, Y. (2015) Phase transition of spindle-associated protein regulate spindle apparatus assembly. Cell, 163(1), 108-122. PMID: 26388440


There are 34 genes.  Reviewed (0 or Unreviewed (34

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Lac-1698
ENSLACG00000011384.1
H3ATF5
2
LLPS-Lac-2374
ENSLACG00000000281.1
H2ZSE1
3
LLPS-Lac-2772
ENSLACG00000016133.1
H3B8U3
4
LLPS-Lac-3492
ENSLACG00000010573.1
H3AQU2
5
LLPS-Lac-2942
ENSLACG00000004327.1
H3A5E8
CKAP2
6
LLPS-Lac-2878
ENSLACG00000018814.1
H3BHP1
CKAP5
7
LLPS-Lac-2065
ENSLACG00000014954.1
H3B509
CLTB
8
LLPS-Lac-1502
ENSLACG00000000245.2
H2ZSA2
DCTN3
9
LLPS-Lac-2720
ENSLACG00000017733.1
H3BE55
DPYSL2
10
LLPS-Lac-2079
ENSLACG00000005862.1
H3AAE0
EZR
11
LLPS-Lac-0062
ENSLACG00000013166.1
H3AZ88
GPSM2
12
LLPS-Lac-3356
ENSLACG00000008680.2
H3AJM4
HAUS3
13
LLPS-Lac-3076
ENSLACG00000010730.1
H3ARC2
KAT14
14
LLPS-Lac-1765
ENSLACG00000008486.1
H3AJ02
KATNAL1
15
LLPS-Lac-0936
ENSLACG00000013547.2
H3B0G7
KIF11
16
LLPS-Lac-2993
ENSLACG00000004309.1
H3A5C5
LOC102345465
17
LLPS-Lac-3057
ENSLACG00000001928.1
H2ZXN7
LOC102348752
18
LLPS-Lac-3994
ENSLACG00000014936.1
H3B4Y9
LOC102355470
19
LLPS-Lac-0184
ENSLACG00000007572.2
H3AFY8
MAD2L1
20
LLPS-Lac-2277
ENSLACG00000019153.1
H3BIS4
MAD2L2
21
LLPS-Lac-2665
ENSLACG00000001524.1
H2ZWD2
MAPK6
22
LLPS-Lac-1382
ENSLACG00000015913.1
H3B840
MAPRE3
23
LLPS-Lac-0949
ENSLACG00000009786.1
H3ANA2
MARVELD1
24
LLPS-Lac-0534
ENSLACG00000015271.1
H3B617
MKNK1
25
LLPS-Lac-3251
ENSLACG00000005355.1
H3A8R1
NCOA4
26
LLPS-Lac-2640
ENSLACG00000015045.1
H3B5A2
PARD3
27
LLPS-Lac-2067
ENSLACG00000003845.1
H3A3V0
RANBP9
28
LLPS-Lac-0047
ENSLACG00000015335.1
H3B688
SEPT2
29
LLPS-Lac-0848
ENSLACG00000010591.1
H3AQW1
SMC3
30
LLPS-Lac-0628
ENSLACG00000000067.1
H2ZRQ6
TADA3
31
LLPS-Lac-2298
ENSLACG00000011833.1
H3AUX2
TMEM201
32
LLPS-Lac-0528
ENSLACG00000015441.1
H3B6L0
TPR
33
LLPS-Lac-0066
ENSLACG00000012702.1
H3AXR4
ZBTB4
34
LLPS-Lac-3706
ENSLACG00000016289.1
H3B9D1
ZNF207