Ictidomys tridecemlineatus      Spindle apparatus


※ Spindle apparatus introduction

    The spindle is an important structure when cells divide. Phase separation promotes the concentration of molecules into the droplets, thereby promoting biochemical reactions. Some protein mixtures undergo a phase change to form droplets that concentrate actin to promote F-actin assembly in vitro. In addition, studies have shown that the phase transition of spindle regulatory protein BuGZ concentrates tubulin and promotes MT polymerizationbinds to tubulin and promotes spindle assembly (1).

Reference
1. Jiang, H., Wang, S., Huang, Y., He, X., Cui, H., Zhu, X., & Zheng, Y. (2015) Phase transition of spindle-associated protein regulate spindle apparatus assembly. Cell, 163(1), 108-122. PMID: 26388440


There are 37 genes.  Reviewed (0 or Unreviewed (37

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Ict-1487
ENSSTOG00000034713.1
A0A287CT70
2
LLPS-Ict-0434
ENSSTOG00000011958.3
I3MIA4
Aurka
3
LLPS-Ict-3804
ENSSTOG00000004716.3
I3M4S2
CDC6
4
LLPS-Ict-2879
ENSSTOG00000013811.3
I3NAB7
CHAMP1
5
LLPS-Ict-1189
ENSSTOG00000022334.2
I3MTD9
CKAP2
6
LLPS-Ict-0302
ENSSTOG00000005158.3
A0A287D2T2
CKAP5
7
LLPS-Ict-4476
ENSSTOG00000020362.2
I3N4U7
CLTB
8
LLPS-Ict-2093
ENSSTOG00000002815.3
A0A287CXP0
DCTN3
9
LLPS-Ict-0949
ENSSTOG00000004052.3
I3M3I9
DPYSL2
10
LLPS-Ict-4274
ENSSTOG00000006353.3
I3M7Q9
DYRK3
11
LLPS-Ict-2730
ENSSTOG00000014829.3
I3MNM8
FES
12
LLPS-Ict-4184
ENSSTOG00000006043.3
I3M768
GPSM2
13
LLPS-Ict-3674
ENSSTOG00000020375.2
I3N2G3
HAUS3
14
LLPS-Ict-4030
ENSSTOG00000023239.2
I3NAD0
HAUS6
15
LLPS-Ict-2855
ENSSTOG00000010238.3
I3MF49
KAT14
16
LLPS-Ict-2642
ENSSTOG00000008802.3
I3MCC2
KATNAL1
17
LLPS-Ict-1404
ENSSTOG00000006209.3
I3M7H6
KIF11
18
LLPS-Ict-0401
ENSSTOG00000021862.1
I3NAK2
LOC101968951
19
LLPS-Ict-2389
ENSSTOG00000030757.1
A0A287CZ86
LOC101974667
20
LLPS-Ict-1148
ENSSTOG00000025410.2
I3NDI5
MAD2L1
21
LLPS-Ict-2790
ENSSTOG00000009961.3
I3MEK0
MAD2L2
22
LLPS-Ict-0881
ENSSTOG00000013341.3
I3MKT8
MSN
23
LLPS-Ict-1962
ENSSTOG00000005494.3
A0A287DFB7
MTOR
24
LLPS-Ict-1965
ENSSTOG00000019969.2
I3MZH8
MTUS1
25
LLPS-Ict-4371
ENSSTOG00000026852.2
I3MRV9
NCOA4
26
LLPS-Ict-1173
ENSSTOG00000015301.3
I3MPJ4
PARD3
27
LLPS-Ict-2369
ENSSTOG00000002829.3
A0A287DG86
RANBP10
28
LLPS-Ict-3715
ENSSTOG00000026546.2
I3M2S9
RBPMS
29
LLPS-Ict-0300
ENSSTOG00000013357.3
I3MKU8
SEPT2
30
LLPS-Ict-0251
ENSSTOG00000030449.1
A0A287DGG8
SMC3
31
LLPS-Ict-3177
ENSSTOG00000003895.3
I3M385
SUN1
32
LLPS-Ict-1989
ENSSTOG00000026929.2
I3MTN3
SUN2
33
LLPS-Ict-2054
ENSSTOG00000002107.3
I3LZS5
TADA3
34
LLPS-Ict-3688
ENSSTOG00000023478.2
I3N3U9
TMEM201
35
LLPS-Ict-2114
ENSSTOG00000013941.3
I3MM33
TPR
36
LLPS-Ict-0739
ENSSTOG00000000346.3
A0A287D0H1
Zbtb4
37
LLPS-Ict-0094
ENSSTOG00000000712.3
I3LX75
Znf207