Erinaceus europaeus      Spindle apparatus


※ Spindle apparatus introduction

    The spindle is an important structure when cells divide. Phase separation promotes the concentration of molecules into the droplets, thereby promoting biochemical reactions. Some protein mixtures undergo a phase change to form droplets that concentrate actin to promote F-actin assembly in vitro. In addition, studies have shown that the phase transition of spindle regulatory protein BuGZ concentrates tubulin and promotes MT polymerizationbinds to tubulin and promotes spindle assembly (1).

Reference
1. Jiang, H., Wang, S., Huang, Y., He, X., Cui, H., Zhu, X., & Zheng, Y. (2015) Phase transition of spindle-associated protein regulate spindle apparatus assembly. Cell, 163(1), 108-122. PMID: 26388440


There are 6 genes.  Reviewed (0 or Unreviewed (6

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Ere-0712
ENSEEUG00000006980.1
A0A1S3WW36
CHAMP1
2
LLPS-Ere-0638
ENSEEUG00000001574.1
A0A1S3WJ44
LOC103118989
3
LLPS-Ere-0019
ENSEEUG00000009629.1
A0A1S3AB98
MAD2L1
4
LLPS-Ere-0907
ENSEEUG00000005918.1
A0A1S3WNZ8
MAD2L2
5
LLPS-Ere-0043
ENSEEUG00000006743.1
A0A1S2ZL14
MAPRE2
6
LLPS-Ere-0025
ENSEEUG00000002290.1
A0A1S2ZPU6
SPAG4