Dothistroma septosporum      Spindle apparatus


※ Spindle apparatus introduction

    The spindle is an important structure when cells divide. Phase separation promotes the concentration of molecules into the droplets, thereby promoting biochemical reactions. Some protein mixtures undergo a phase change to form droplets that concentrate actin to promote F-actin assembly in vitro. In addition, studies have shown that the phase transition of spindle regulatory protein BuGZ concentrates tubulin and promotes MT polymerizationbinds to tubulin and promotes spindle assembly (1).

Reference
1. Jiang, H., Wang, S., Huang, Y., He, X., Cui, H., Zhu, X., & Zheng, Y. (2015) Phase transition of spindle-associated protein regulate spindle apparatus assembly. Cell, 163(1), 108-122. PMID: 26388440


There are 7 genes.  Reviewed (0 or Unreviewed (7

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Dos-0365
DOTSEDRAFT_40227
N1Q2U2
DOTSEDRAFT_40227
2
LLPS-Dos-0169
DOTSEDRAFT_51741
N1PRV4
DOTSEDRAFT_51741
3
LLPS-Dos-0649
DOTSEDRAFT_56948
M2XJJ1
DOTSEDRAFT_56948
4
LLPS-Dos-1293
DOTSEDRAFT_70504
N1PVY4
DOTSEDRAFT_70504
5
LLPS-Dos-1545
DOTSEDRAFT_70683
N1PX48
DOTSEDRAFT_70683
6
LLPS-Dos-0286
DOTSEDRAFT_70796
N1PN48
DOTSEDRAFT_70796
7
LLPS-Dos-1173
DOTSEDRAFT_74488
N1PEZ5
DOTSEDRAFT_74488