Dipodomys ordii      Spindle apparatus


※ Spindle apparatus introduction

    The spindle is an important structure when cells divide. Phase separation promotes the concentration of molecules into the droplets, thereby promoting biochemical reactions. Some protein mixtures undergo a phase change to form droplets that concentrate actin to promote F-actin assembly in vitro. In addition, studies have shown that the phase transition of spindle regulatory protein BuGZ concentrates tubulin and promotes MT polymerizationbinds to tubulin and promotes spindle assembly (1).

Reference
1. Jiang, H., Wang, S., Huang, Y., He, X., Cui, H., Zhu, X., & Zheng, Y. (2015) Phase transition of spindle-associated protein regulate spindle apparatus assembly. Cell, 163(1), 108-122. PMID: 26388440


There are 30 genes.  Reviewed (0 or Unreviewed (30

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Dio-3991
ENSDORG00000015184.2
A0A1S3GUY8
Cdc6
2
LLPS-Dio-1443
ENSDORG00000024164.1
A0A1S3FNX9
Champ1
3
LLPS-Dio-4344
ENSDORG00000002476.2
A0A1S3GQS9
Ckap2
4
LLPS-Dio-2608
ENSDORG00000011373.2
A0A1S3GBL7
Ckap5
5
LLPS-Dio-4328
ENSDORG00000013195.2
A0A1S3G2Q4
Csrp2bp
6
LLPS-Dio-1677
ENSDORG00000001720.2
A0A1S3G1T7
Dctn3
7
LLPS-Dio-3093
ENSDORG00000027913.1
A0A1S3ETC1
Dlgap5
8
LLPS-Dio-0281
ENSDORG00000023604.1
A0A1S3GM57
Dpysl2
9
LLPS-Dio-3508
ENSDORG00000011083.2
A0A1S3F8C6
Dyrk3
10
LLPS-Dio-3428
ENSDORG00000012649.2
A0A1S3FS46
Haus3
11
LLPS-Dio-2172
ENSDORG00000026577.1
A0A1S3FIS3
Haus6
12
LLPS-Dio-0651
ENSDORG00000012794.2
A0A1S3G3W0
Katnal1
13
LLPS-Dio-0227
ENSDORG00000008541.2
A0A1S3GLU1
Kif11
14
LLPS-Dio-2021
ENSDORG00000011019.2
A0A1S3EPB5
LOC105981225
15
LLPS-Dio-1079
ENSDORG00000000355.2
A0A1S3FNI1
Mad2l1
16
LLPS-Dio-4091
ENSDORG00000008092.2
A0A1S3GPZ4
Mad2l2
17
LLPS-Dio-0374
ENSDORG00000023413.1
A0A1S3ESK9
Mapre1
18
LLPS-Dio-2568
ENSDORG00000007207.2
A0A1S3F8M7
Mknk1
19
LLPS-Dio-0901
ENSDORG00000016668.2
A0A1S3GLJ9
Msn
20
LLPS-Dio-2784
ENSDORG00000003771.2
A0A1S3GF08
Mtor
21
LLPS-Dio-1225
ENSDORG00000023741.1
A0A1S3FX86
Mtus1
22
LLPS-Dio-2188
ENSDORG00000004934.2
A0A1S3GUN3
Ncoa4
23
LLPS-Dio-0416
ENSDORG00000000366.2
A0A1S3EK70
Pard3
24
LLPS-Dio-2520
ENSDORG00000010698.2
A0A1S3EX40
Ranbp10
25
LLPS-Dio-0563
ENSDORG00000023373.1
A0A1S3ELZ0
Rbpms2
26
LLPS-Dio-2229
ENSDORG00000000106.2
A0A1S3GMA1
Sept2
27
LLPS-Dio-2354
ENSDORG00000029811.1
A0A1S3F937
Smc3
28
LLPS-Dio-2006
ENSDORG00000002734.2
A0A1S3FSC8
Sun1
29
LLPS-Dio-2000
ENSDORG00000015797.2
A0A1S3FUU3
Sun2
30
LLPS-Dio-3657
ENSDORG00000007139.2
A0A1S3F5R8
Znf207