Danio rerio      Spindle apparatus


※ Spindle apparatus introduction

    The spindle is an important structure when cells divide. Phase separation promotes the concentration of molecules into the droplets, thereby promoting biochemical reactions. Some protein mixtures undergo a phase change to form droplets that concentrate actin to promote F-actin assembly in vitro. In addition, studies have shown that the phase transition of spindle regulatory protein BuGZ concentrates tubulin and promotes MT polymerizationbinds to tubulin and promotes spindle assembly (1).

Reference
1. Jiang, H., Wang, S., Huang, Y., He, X., Cui, H., Zhu, X., & Zheng, Y. (2015) Phase transition of spindle-associated protein regulate spindle apparatus assembly. Cell, 163(1), 108-122. PMID: 26388440


There are 35 genes.  Reviewed (1 or Unreviewed (34

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Dar-0005
ENSDARG00000079578.5
Q7ZUL7
rbpms2b
2
LLPS-Dar-0891
ENSDARG00000110804.1
A0A2R8QIS2
3
LLPS-Dar-0492
ENSDARG00000012485.8
F1QEM3
aurka
4
LLPS-Dar-1998
ENSDARG00000009942.9
F1R1N7
cdc6
5
LLPS-Dar-1578
ENSDARG00000102674.2
A0A0R4IA93
ckap5
6
LLPS-Dar-3914
ENSDARG00000052368.8
A0A286Y9F1
cltb
7
LLPS-Dar-0420
ENSDARG00000041363.7
Q6GQL6
dctn3
8
LLPS-Dar-1456
ENSDARG00000045167.7
F1Q687
dlgap5
9
LLPS-Dar-0996
ENSDARG00000038974.8
A0A2R8Q6T7
dpysl2a
10
LLPS-Dar-4008
ENSDARG00000025091.11
Q5TZG5
ezrb
11
LLPS-Dar-3443
ENSDARG00000011449.13
A0A2R8Q7T0
fes
12
LLPS-Dar-1975
ENSDARG00000011652.11
K7DY47
ftr52p
13
LLPS-Dar-1247
ENSDARG00000017311.11
F1R646
gpsm2
14
LLPS-Dar-4190
ENSDARG00000061385.9
A0A2R8Q1K1
haus3
15
LLPS-Dar-2644
ENSDARG00000041708.9
Q1LXR5
kat14
16
LLPS-Dar-3289
ENSDARG00000099156.2
Q5U3S1
katnal1
17
LLPS-Dar-0144
ENSDARG00000010948.11
F1QK82
kif11
18
LLPS-Dar-0092
ENSDARG00000004713.7
F1QHN1
mad2l1
19
LLPS-Dar-3095
ENSDARG00000042456.6
Q568H3
mad2l2
20
LLPS-Dar-2420
ENSDARG00000032103.10
Q0H1F2
mapk6
21
LLPS-Dar-0343
ENSDARG00000102878.2
Q6GMJ3
mapre3b
22
LLPS-Dar-3717
ENSDARG00000011724.8
Q5BLB7
marveld1
23
LLPS-Dar-2378
ENSDARG00000018411.10
F1QJV2
mknk1
24
LLPS-Dar-3151
ENSDARG00000053196.8
B0UX67
mtor
25
LLPS-Dar-2437
ENSDARG00000115363.1
A0JMQ7
mtus1a
26
LLPS-Dar-4234
ENSDARG00000021439.9
Q6P0F7
ncoa4
27
LLPS-Dar-0451
ENSDARG00000062138.7
Q1LUS8
ranbp10
28
LLPS-Dar-1387
ENSDARG00000041317.6
Q08BV5
rangap1a
29
LLPS-Dar-3666
ENSDARG00000094540.3
A2BFV6
si:dkey-96l17.6
30
LLPS-Dar-1468
ENSDARG00000019000.10
Q1LVV8
smc3
31
LLPS-Dar-1546
ENSDARG00000113214.1
Q7SY21
tada3
32
LLPS-Dar-0633
ENSDARG00000077307.5
A4IG66
tmem201
33
LLPS-Dar-0711
ENSDARG00000016630.10
Q5RI09
tprb
34
LLPS-Dar-1124
ENSDARG00000078654.5
E9QE51
tpx2
35
LLPS-Dar-2643
ENSDARG00000110098.1
Q6P0T6
znf207b