Cyanidioschyzon merolae      Spindle apparatus


※ Spindle apparatus introduction

    The spindle is an important structure when cells divide. Phase separation promotes the concentration of molecules into the droplets, thereby promoting biochemical reactions. Some protein mixtures undergo a phase change to form droplets that concentrate actin to promote F-actin assembly in vitro. In addition, studies have shown that the phase transition of spindle regulatory protein BuGZ concentrates tubulin and promotes MT polymerizationbinds to tubulin and promotes spindle assembly (1).

Reference
1. Jiang, H., Wang, S., Huang, Y., He, X., Cui, H., Zhu, X., & Zheng, Y. (2015) Phase transition of spindle-associated protein regulate spindle apparatus assembly. Cell, 163(1), 108-122. PMID: 26388440


There are 8 genes.  Reviewed (0 or Unreviewed (8

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Cym-0385
CMC157C
M1V6M6
CYME_CMC157C
2
LLPS-Cym-0028
CMG035C
M1V775
CYME_CMG035C
3
LLPS-Cym-0150
CML027C
M1V5H1
CYME_CML027C
4
LLPS-Cym-0399
CMO196C
M1UUK0
CYME_CMO196C
5
LLPS-Cym-0489
CMP130C
M1UV39
CYME_CMP130C
6
LLPS-Cym-0752
CMP137C
M1UV45
CYME_CMP137C
7
LLPS-Cym-0237
CMQ044C
M1VA81
CYME_CMQ044C
8
LLPS-Cym-0508
CMS347C
M1VM30
CYME_CMS347C