Cryptococcus neoformans      Spindle apparatus


※ Spindle apparatus introduction

    The spindle is an important structure when cells divide. Phase separation promotes the concentration of molecules into the droplets, thereby promoting biochemical reactions. Some protein mixtures undergo a phase change to form droplets that concentrate actin to promote F-actin assembly in vitro. In addition, studies have shown that the phase transition of spindle regulatory protein BuGZ concentrates tubulin and promotes MT polymerizationbinds to tubulin and promotes spindle assembly (1).

Reference
1. Jiang, H., Wang, S., Huang, Y., He, X., Cui, H., Zhu, X., & Zheng, Y. (2015) Phase transition of spindle-associated protein regulate spindle apparatus assembly. Cell, 163(1), 108-122. PMID: 26388440


There are 10 genes.  Reviewed (0 or Unreviewed (10

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Crn-0712
CNC01510
Q5KKX5
CNC01510
2
LLPS-Crn-1187
CNC07120
Q5KJB5
CNC07120
3
LLPS-Crn-1394
CND02930
Q5KIH7
CND02930
4
LLPS-Crn-0513
CNG01340
Q5KE89
CNG01340
5
LLPS-Crn-0509
CNG02140
Q5KE09
CNG02140
6
LLPS-Crn-0254
CNH03255
A0A0S2M5S4
CNH03255
7
LLPS-Crn-0971
CNJ01070
Q5KAN5
CNJ01070
8
LLPS-Crn-1318
CNL04090
Q5K8Y1
CNL04090
9
LLPS-Crn-0064
CNN00070
Q5K7F0
CNN00070
10
LLPS-Crn-1175
CNN01005
A0A0S2M675
CNN01005