Chondrus crispus      Spindle apparatus


※ Spindle apparatus introduction

    The spindle is an important structure when cells divide. Phase separation promotes the concentration of molecules into the droplets, thereby promoting biochemical reactions. Some protein mixtures undergo a phase change to form droplets that concentrate actin to promote F-actin assembly in vitro. In addition, studies have shown that the phase transition of spindle regulatory protein BuGZ concentrates tubulin and promotes MT polymerizationbinds to tubulin and promotes spindle assembly (1).

Reference
1. Jiang, H., Wang, S., Huang, Y., He, X., Cui, H., Zhu, X., & Zheng, Y. (2015) Phase transition of spindle-associated protein regulate spindle apparatus assembly. Cell, 163(1), 108-122. PMID: 26388440


There are 8 genes.  Reviewed (0 or Unreviewed (8

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Chc-0228
CHC_T00002018001
R7Q716
CHC_T00002018001
2
LLPS-Chc-0843
CHC_T00002178001
R7Q5W4
CHC_T00002178001
3
LLPS-Chc-0075
CHC_T00004920001
R7QFW2
CHC_T00004920001
4
LLPS-Chc-0295
CHC_T00004956001
R7QFX1
CHC_T00004956001
5
LLPS-Chc-0315
CHC_T00006529001
R7QM00
CHC_T00006529001
6
LLPS-Chc-0014
CHC_T00006718001
R7QNH4
CHC_T00006718001
7
LLPS-Chc-0866
CHC_T00008776001
R7QC59
CHC_T00008776001
8
LLPS-Chc-0757
CHC_T00009288001
R7QSN9
CHC_T00009288001