Chlorocebus sabaeus      Spindle apparatus


※ Spindle apparatus introduction

    The spindle is an important structure when cells divide. Phase separation promotes the concentration of molecules into the droplets, thereby promoting biochemical reactions. Some protein mixtures undergo a phase change to form droplets that concentrate actin to promote F-actin assembly in vitro. In addition, studies have shown that the phase transition of spindle regulatory protein BuGZ concentrates tubulin and promotes MT polymerizationbinds to tubulin and promotes spindle assembly (1).

Reference
1. Jiang, H., Wang, S., Huang, Y., He, X., Cui, H., Zhu, X., & Zheng, Y. (2015) Phase transition of spindle-associated protein regulate spindle apparatus assembly. Cell, 163(1), 108-122. PMID: 26388440


There are 41 genes.  Reviewed (0 or Unreviewed (41

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Chs-0536
ENSCSAG00000003731.1
A0A0D9QUR3
2
LLPS-Chs-2206
ENSCSAG00000000114.1
A0A0D9SAI8
3
LLPS-Chs-3639
ENSCSAG00000015393.1
A0A0D9RS62
AURKA
4
LLPS-Chs-0501
ENSCSAG00000010702.1
A0A0D9RE88
AURKB
5
LLPS-Chs-4355
ENSCSAG00000002784.1
A0A0D9S323
CDC6
6
LLPS-Chs-0592
ENSCSAG00000000209.1
A0A0D9SA97
CHAMP1
7
LLPS-Chs-1404
ENSCSAG00000017670.1
A0A0D9RYK4
CKAP2
8
LLPS-Chs-2157
ENSCSAG00000005686.1
A0A0D9R056
CKAP5
9
LLPS-Chs-3597
ENSCSAG00000009357.1
A0A0D9RAG9
CLTB
10
LLPS-Chs-3168
ENSCSAG00000010136.1
A0A0D9RCN6
DCTN3
11
LLPS-Chs-0747
ENSCSAG00000014651.1
A0A0D9RQ86
DLGAP5
12
LLPS-Chs-3172
ENSCSAG00000016049.1
A0A0D9RU31
DPYSL2
13
LLPS-Chs-3869
ENSCSAG00000014943.1
A0A0D9RR10
DYRK3
14
LLPS-Chs-2923
ENSCSAG00000017051.1
A0A0D9RWV5
FES
15
LLPS-Chs-4172
ENSCSAG00000001535.1
A0A0D9S6K4
GPSM2
16
LLPS-Chs-1759
ENSCSAG00000015734.1
A0A0D9RT80
HAUS3
17
LLPS-Chs-3612
ENSCSAG00000009348.1
A0A0D9RAG0
HAUS6
18
LLPS-Chs-3078
ENSCSAG00000011539.1
A0A0D9RGK0
KAT14
19
LLPS-Chs-0665
ENSCSAG00000017958.1
A0A0D9RZD9
KATNAL1
20
LLPS-Chs-0558
ENSCSAG00000006555.1
A0A0D9R2K0
KIF11
21
LLPS-Chs-1326
ENSCSAG00000000797.1
A0A0D9S8M0
MAD2L2
22
LLPS-Chs-2908
ENSCSAG00000011360.1
A0A0D9RG14
MAPK6
23
LLPS-Chs-0526
ENSCSAG00000012529.1
A0A0D9RJC4
MAPRE1
24
LLPS-Chs-1732
ENSCSAG00000018448.1
A0A0D9SAV1
MARVELD1
25
LLPS-Chs-0400
ENSCSAG00000001237.1
A0A0D9S7D8
MKNK1
26
LLPS-Chs-2489
ENSCSAG00000011947.1
A0A0D9RHQ0
MSN
27
LLPS-Chs-1233
ENSCSAG00000000790.1
A0A0D9S8M7
MTOR
28
LLPS-Chs-3171
ENSCSAG00000016743.1
A0A0D9RW14
MTUS1
29
LLPS-Chs-3627
ENSCSAG00000010529.1
A0A0D9RDP2
NCOA4
30
LLPS-Chs-1859
ENSCSAG00000011392.1
A0A0D9RG50
PARD3
31
LLPS-Chs-2291
ENSCSAG00000015838.1
A0A0D9RTH8
RBPMS
32
LLPS-Chs-3712
ENSCSAG00000005773.1
A0A0D9R0E2
SEPT2
33
LLPS-Chs-1363
ENSCSAG00000005160.1
A0A0D9QYP0
SMC3
34
LLPS-Chs-1978
ENSCSAG00000017541.1
A0A0D9RY80
SUN1
35
LLPS-Chs-1879
ENSCSAG00000006487.1
A0A0D9R2D4
SUN2
36
LLPS-Chs-3409
ENSCSAG00000010578.1
A0A0D9RDW3
TADA3
37
LLPS-Chs-4449
ENSCSAG00000000769.1
A0A0D9S8P8
TMEM201
38
LLPS-Chs-2454
ENSCSAG00000013292.1
A0A0D9RLG8
TPR
39
LLPS-Chs-1192
ENSCSAG00000002706.1
A0A0D9S3A0
TUBB3
40
LLPS-Chs-2159
ENSCSAG00000011692.1
A0A0D9RH00
ZBTB4
41
LLPS-Chs-4223
ENSCSAG00000006379.1
A0A0D9R230
ZNF207