Canis familiaris      Spindle apparatus


※ Spindle apparatus introduction

    The spindle is an important structure when cells divide. Phase separation promotes the concentration of molecules into the droplets, thereby promoting biochemical reactions. Some protein mixtures undergo a phase change to form droplets that concentrate actin to promote F-actin assembly in vitro. In addition, studies have shown that the phase transition of spindle regulatory protein BuGZ concentrates tubulin and promotes MT polymerizationbinds to tubulin and promotes spindle assembly (1).

Reference
1. Jiang, H., Wang, S., Huang, Y., He, X., Cui, H., Zhu, X., & Zheng, Y. (2015) Phase transition of spindle-associated protein regulate spindle apparatus assembly. Cell, 163(1), 108-122. PMID: 26388440


There are 39 genes.  Reviewed (0 or Unreviewed (39

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Caf-0570
ENSCAFG00000023297.1
F1PM71
AURKC
2
LLPS-Caf-0843
ENSCAFG00000016106.3
E2R6N1
CDC6
3
LLPS-Caf-2502
ENSCAFG00000006507.3
J9P0P7
CHAMP1
4
LLPS-Caf-0934
ENSCAFG00000005898.3
F1PIR7
CKAP2
5
LLPS-Caf-0127
ENSCAFG00000009053.3
E2RSW0
CKAP5
6
LLPS-Caf-4490
ENSCAFG00000016689.3
F6X5M3
CLTB
7
LLPS-Caf-2338
ENSCAFG00000001937.3
E2RBC1
DCTN3
8
LLPS-Caf-0984
ENSCAFG00000015026.4
F1PWI6
DLGAP5
9
LLPS-Caf-1232
ENSCAFG00000008753.3
F1P9U4
DPYSL2
10
LLPS-Caf-1974
ENSCAFG00000011429.3
E2R8C3
DYRK3
11
LLPS-Caf-0878
ENSCAFG00000012298.3
F1PUK7
FES
12
LLPS-Caf-2603
ENSCAFG00000019880.3
F6V2B9
GPSM2
13
LLPS-Caf-1404
ENSCAFG00000014883.3
F1PDJ8
HAUS3
14
LLPS-Caf-2342
ENSCAFG00000001598.3
E2RP27
HAUS6
15
LLPS-Caf-1033
ENSCAFG00000005450.3
E2RC51
KAT14
16
LLPS-Caf-0395
ENSCAFG00000006616.3
F6V168
KATNAL1
17
LLPS-Caf-1626
ENSCAFG00000007497.3
E2QXT6
KIF11
18
LLPS-Caf-0423
ENSCAFG00000016467.3
E2R3U8
MAD2L1
19
LLPS-Caf-2727
ENSCAFG00000016583.3
F1PGQ8
MAD2L2
20
LLPS-Caf-2259
ENSCAFG00000015640.4
E2QVF3
MAPK6
21
LLPS-Caf-1778
ENSCAFG00000007306.3
F6Y5Z5
MAPRE1
22
LLPS-Caf-2904
ENSCAFG00000031220.1
J9P258
MARVELD1
23
LLPS-Caf-2493
ENSCAFG00000004205.4
F1PPH9
MKNK1
24
LLPS-Caf-4194
ENSCAFG00000016607.3
E2R7F1
MSN
25
LLPS-Caf-2282
ENSCAFG00000016648.4
E2R2L2
MTOR
26
LLPS-Caf-3548
ENSCAFG00000006979.4
E2RCA9
MTUS1
27
LLPS-Caf-0725
ENSCAFG00000006809.3
E2RDF1
NCOA4
28
LLPS-Caf-3440
ENSCAFG00000003737.3
F1PFK4
PARD3
29
LLPS-Caf-3883
ENSCAFG00000020331.5
F1PA66
RANBP10
30
LLPS-Caf-3812
ENSCAFG00000006503.3
E2R5F7
RBPMS
31
LLPS-Caf-2665
ENSCAFG00000012960.3
F1PEK5
SEPT2
32
LLPS-Caf-0120
ENSCAFG00000010762.3
E2R7T4
SMC3
33
LLPS-Caf-4327
ENSCAFG00000011273.4
E2R8J5
SUN1
34
LLPS-Caf-2724
ENSCAFG00000001371.4
E2RL48
SUN2
35
LLPS-Caf-1067
ENSCAFG00000005324.3
E2R4K1
TADA3
36
LLPS-Caf-4013
ENSCAFG00000019733.4
F1PE94
TMEM201
37
LLPS-Caf-1282
ENSCAFG00000013717.3
F6UV28
TPR
38
LLPS-Caf-1266
ENSCAFG00000016341.4
E2QZ31
ZBTB4
39
LLPS-Caf-3534
ENSCAFG00000018403.4
F1PRK3
ZNF207