Bos taurus      Spindle apparatus


※ Spindle apparatus introduction

    The spindle is an important structure when cells divide. Phase separation promotes the concentration of molecules into the droplets, thereby promoting biochemical reactions. Some protein mixtures undergo a phase change to form droplets that concentrate actin to promote F-actin assembly in vitro. In addition, studies have shown that the phase transition of spindle regulatory protein BuGZ concentrates tubulin and promotes MT polymerizationbinds to tubulin and promotes spindle assembly (1).

Reference
1. Jiang, H., Wang, S., Huang, Y., He, X., Cui, H., Zhu, X., & Zheng, Y. (2015) Phase transition of spindle-associated protein regulate spindle apparatus assembly. Cell, 163(1), 108-122. PMID: 26388440


There are 41 genes.  Reviewed (2 or Unreviewed (39

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Bot-0140
ENSBTAG00000002608.6
Q2NKY7
SEPT2
2
LLPS-Bot-0135
ENSBTAG00000013905.6
A7Z065
SMC3
3
LLPS-Bot-1292
ENSBTAG00000024874.5
4
LLPS-Bot-1417
ENSBTAG00000013009.6
Q2TA06
AURKA
5
LLPS-Bot-1611
ENSBTAG00000003261.6
F1MY86
AURKC
6
LLPS-Bot-3024
ENSBTAG00000010384.5
E1BAQ1
CDC6
7
LLPS-Bot-3499
ENSBTAG00000020861.5
F1MFQ9
CHAMP1
8
LLPS-Bot-4483
ENSBTAG00000021162.6
F1MBA0
CKAP2
9
LLPS-Bot-1804
ENSBTAG00000004448.6
E1B7K5
CKAP5
10
LLPS-Bot-3354
ENSBTAG00000010740.6
P04975
CLTB
11
LLPS-Bot-1697
ENSBTAG00000018883.6
Q0P5A1
DCTN3
12
LLPS-Bot-0844
ENSBTAG00000002331.6
Q08DQ9
DLGAP5
13
LLPS-Bot-3366
ENSBTAG00000018373.5
O02675
DPYSL2
14
LLPS-Bot-4677
ENSBTAG00000013294.4
F6PR52
DYRK3
15
LLPS-Bot-4168
ENSBTAG00000002941.5
Q5E9H3
FES
16
LLPS-Bot-2972
ENSBTAG00000017124.6
E1BIX7
GPSM2
17
LLPS-Bot-2319
ENSBTAG00000024787.5
F1MNN1
HAUS3
18
LLPS-Bot-0718
ENSBTAG00000018978.6
E1BE91
KAT14
19
LLPS-Bot-2822
ENSBTAG00000009340.6
F1MAX6
KATNAL1
20
LLPS-Bot-1057
ENSBTAG00000009383.6
E1BF29
KIF11
21
LLPS-Bot-2954
ENSBTAG00000013275.5
F1MSW4
MAD2L2
22
LLPS-Bot-0707
ENSBTAG00000005865.4
G5E577
MAPK6
23
LLPS-Bot-1671
ENSBTAG00000003908.6
Q3ZBD9
MAPRE1
24
LLPS-Bot-1491
ENSBTAG00000013478.4
A7MB03
MARVELD1
25
LLPS-Bot-1206
ENSBTAG00000019933.6
F1N1A7
MKNK1
26
LLPS-Bot-2324
ENSBTAG00000003418.5
Q2HJ49
MSN
27
LLPS-Bot-2178
ENSBTAG00000015325.6
E1BFB4
MTOR
28
LLPS-Bot-4037
ENSBTAG00000039682.4
Q17QT2
MTUS1
29
LLPS-Bot-0787
ENSBTAG00000019565.5
Q1RMQ8
NCOA4
30
LLPS-Bot-1104
ENSBTAG00000015986.6
A6QLS4
NDE1
31
LLPS-Bot-3926
ENSBTAG00000014991.6
F1MZ23
PARD3
32
LLPS-Bot-0615
ENSBTAG00000018643.6
F1MRT3
PRC1
33
LLPS-Bot-1317
ENSBTAG00000032763.4
F1MSI0
RANBP10
34
LLPS-Bot-1039
ENSBTAG00000033727.4
F1MAV3
RBPMS
35
LLPS-Bot-0619
ENSBTAG00000046498.2
G3MWU2
SUN1
36
LLPS-Bot-1542
ENSBTAG00000003693.6
A6QLV1
SUN2
37
LLPS-Bot-1625
ENSBTAG00000007961.6
Q5EAE2
TADA3
38
LLPS-Bot-0867
ENSBTAG00000003180.6
F1N0C3
TMEM201
39
LLPS-Bot-2128
ENSBTAG00000023730.3
Q2T9S0
TUBB3
40
LLPS-Bot-1637
ENSBTAG00000008289.6
F1MFQ4
ZBTB4
41
LLPS-Bot-1760
ENSBTAG00000008883.6
F1MVH9
ZNF207