Aspergillus nidulans      Spindle apparatus


※ Spindle apparatus introduction

    The spindle is an important structure when cells divide. Phase separation promotes the concentration of molecules into the droplets, thereby promoting biochemical reactions. Some protein mixtures undergo a phase change to form droplets that concentrate actin to promote F-actin assembly in vitro. In addition, studies have shown that the phase transition of spindle regulatory protein BuGZ concentrates tubulin and promotes MT polymerizationbinds to tubulin and promotes spindle assembly (1).

Reference
1. Jiang, H., Wang, S., Huang, Y., He, X., Cui, H., Zhu, X., & Zheng, Y. (2015) Phase transition of spindle-associated protein regulate spindle apparatus assembly. Cell, 163(1), 108-122. PMID: 26388440


There are 12 genes.  Reviewed (0 or Unreviewed (12

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Asn-0007
ANIA_05521
Q5B1Q9
alpA
2
LLPS-Asn-0573
ANIA_02128
Q5BBF2
ANIA_02128
3
LLPS-Asn-1426
ANIA_02163
C8VM97
ANIA_02163
4
LLPS-Asn-0364
ANIA_02511
Q5BAB9
ANIA_02511
5
LLPS-Asn-1290
ANIA_04021
Q5B609
ANIA_04021
6
LLPS-Asn-0102
ANIA_04862
Q5B3L8
ANIA_04862
7
LLPS-Asn-0133
ANIA_05499
Q5B1T1
ANIA_05499
8
LLPS-Asn-0737
ANIA_05676
Q5B1A4
ANIA_05676
9
LLPS-Asn-1047
ANIA_11164
C8VH46
ANIA_11164
10
LLPS-Asn-0730
ANIA_03363
P17120
bimC
11
LLPS-Asn-0276
ANIA_06125
O74689
nudE
12
LLPS-Asn-1177
ANIA_06364
Q00737
sudA