Aspergillus fumigatus      Spindle apparatus


※ Spindle apparatus introduction

    The spindle is an important structure when cells divide. Phase separation promotes the concentration of molecules into the droplets, thereby promoting biochemical reactions. Some protein mixtures undergo a phase change to form droplets that concentrate actin to promote F-actin assembly in vitro. In addition, studies have shown that the phase transition of spindle regulatory protein BuGZ concentrates tubulin and promotes MT polymerizationbinds to tubulin and promotes spindle assembly (1).

Reference
1. Jiang, H., Wang, S., Huang, Y., He, X., Cui, H., Zhu, X., & Zheng, Y. (2015) Phase transition of spindle-associated protein regulate spindle apparatus assembly. Cell, 163(1), 108-122. PMID: 26388440


There are 11 genes.  Reviewed (0 or Unreviewed (11

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Asfu-1507
AFUA_1G03710
Q4WK49
AFUA_1G03710
2
LLPS-Asfu-0562
AFUA_1G04590
Q4WJW2
AFUA_1G04590
3
LLPS-Asfu-0757
AFUA_2G14080
Q4X0B2
AFUA_2G14080
4
LLPS-Asfu-1010
AFUA_2G15880
Q4WZT0
AFUA_2G15880
5
LLPS-Asfu-0355
AFUA_2G16260
Q4WZP1
AFUA_2G16260
6
LLPS-Asfu-0394
AFUA_3G14340
Q4WYU9
AFUA_3G14340
7
LLPS-Asfu-0017
AFUA_6G12980
Q4WLM6
AFUA_6G12980
8
LLPS-Asfu-0459
AFUA_6G13120
Q4WLL3
AFUA_6G13120
9
LLPS-Asfu-0045
AFUA_7G01400
Q4WAI2
AFUA_7G01400
10
LLPS-Asfu-1643
AFUA_7G02110
Q4WAQ3
AFUA_7G02110
11
LLPS-Asfu-1115
AFUA_7G04310
Q4WGA1
AFUA_7G04310