Aotus nancymaae      Spindle apparatus


※ Spindle apparatus introduction

    The spindle is an important structure when cells divide. Phase separation promotes the concentration of molecules into the droplets, thereby promoting biochemical reactions. Some protein mixtures undergo a phase change to form droplets that concentrate actin to promote F-actin assembly in vitro. In addition, studies have shown that the phase transition of spindle regulatory protein BuGZ concentrates tubulin and promotes MT polymerizationbinds to tubulin and promotes spindle assembly (1).

Reference
1. Jiang, H., Wang, S., Huang, Y., He, X., Cui, H., Zhu, X., & Zheng, Y. (2015) Phase transition of spindle-associated protein regulate spindle apparatus assembly. Cell, 163(1), 108-122. PMID: 26388440


There are 41 genes.  Reviewed (0 or Unreviewed (41

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Aon-1662
ENSANAG00000038011.1
A0A2K5F7R3
2
LLPS-Aon-1685
ENSANAG00000003067.1
A0A2K5BVB2
3
LLPS-Aon-2932
ENSANAG00000009415.1
A0A2K5BXF7
4
LLPS-Aon-3361
ENSANAG00000010178.1
A0A2K5BYI8
5
LLPS-Aon-3721
ENSANAG00000037303.1
A0A2K5F339
6
LLPS-Aon-1748
ENSANAG00000035885.1
A0A2K5EU53
AURKB
7
LLPS-Aon-4411
ENSANAG00000030612.1
A0A2K5DY33
CDC6
8
LLPS-Aon-0307
ENSANAG00000031111.1
A0A2K5E0M7
CHAMP1
9
LLPS-Aon-0575
ENSANAG00000031236.1
A0A2K5E3A5
CKAP5
10
LLPS-Aon-0148
ENSANAG00000027646.1
A0A2K5DFR4
CLTB
11
LLPS-Aon-2000
ENSANAG00000037331.1
A0A2K5F398
DCTN3
12
LLPS-Aon-1743
ENSANAG00000035817.1
A0A2K5ETP2
DLGAP5
13
LLPS-Aon-0098
ENSANAG00000034307.1
A0A2K5EJR7
DPYSL2
14
LLPS-Aon-1510
ENSANAG00000037904.1
A0A2K5F6R1
DYRK3
15
LLPS-Aon-3360
ENSANAG00000037025.1
A0A2K5F199
FES
16
LLPS-Aon-3250
ENSANAG00000032390.1
A0A2K5E7S7
GPSM2
17
LLPS-Aon-4157
ENSANAG00000029444.1
A0A2K5DQY1
HAUS3
18
LLPS-Aon-4259
ENSANAG00000026527.1
A0A2K5D8P6
HAUS6
19
LLPS-Aon-4495
ENSANAG00000032311.1
A0A2K5E727
KAT14
20
LLPS-Aon-1012
ENSANAG00000037899.1
A0A2K5F6V1
KATNA1
21
LLPS-Aon-0840
ENSANAG00000032354.1
A0A2K5E7M0
KIF11
22
LLPS-Aon-0769
ENSANAG00000022503.1
A0A2K5CK08
MAD2L1
23
LLPS-Aon-3929
ENSANAG00000029506.1
A0A2K5DRE6
MAD2L2
24
LLPS-Aon-3594
ENSANAG00000028054.1
A0A2K5DHY8
MAPK6
25
LLPS-Aon-0448
ENSANAG00000035566.1
A0A2K5ESA4
MAPRE1
26
LLPS-Aon-1659
ENSANAG00000031120.1
A0A2K5E0Q0
MARVELD1
27
LLPS-Aon-0038
ENSANAG00000022817.1
A0A2K5CLW8
MKNK1
28
LLPS-Aon-0489
ENSANAG00000030002.1
A0A2K5DVM4
MTOR
29
LLPS-Aon-1550
ENSANAG00000024799.1
A0A2K5CZC7
PARD3
30
LLPS-Aon-0079
ENSANAG00000020808.1
A0A2K5C9V8
PRC1
31
LLPS-Aon-3438
ENSANAG00000023548.1
A0A2K5CR73
RANBP10
32
LLPS-Aon-2217
ENSANAG00000028150.1
A0A2K5DII8
RBPMS
33
LLPS-Aon-2281
ENSANAG00000023789.1
A0A2K5CSS1
SEPT2
34
LLPS-Aon-2901
ENSANAG00000034789.1
A0A2K5ENW5
SMC3
35
LLPS-Aon-0502
ENSANAG00000021749.1
A0A2K5CFC2
SUN1
36
LLPS-Aon-1399
ENSANAG00000024376.1
A0A2K5CW18
SUN2
37
LLPS-Aon-1777
ENSANAG00000031129.1
A0A2K5E0P2
TADA3
38
LLPS-Aon-1291
ENSANAG00000033261.1
A0A2K5ECZ7
TMEM201
39
LLPS-Aon-0363
ENSANAG00000025007.1
A0A2K5D069
TPR
40
LLPS-Aon-3501
ENSANAG00000030619.1
A0A2K5DXT2
ZBTB4
41
LLPS-Aon-2413
ENSANAG00000033773.1
A0A2K5EGA2
ZNF207