Anolis carolinensis      Spindle apparatus


※ Spindle apparatus introduction

    The spindle is an important structure when cells divide. Phase separation promotes the concentration of molecules into the droplets, thereby promoting biochemical reactions. Some protein mixtures undergo a phase change to form droplets that concentrate actin to promote F-actin assembly in vitro. In addition, studies have shown that the phase transition of spindle regulatory protein BuGZ concentrates tubulin and promotes MT polymerizationbinds to tubulin and promotes spindle assembly (1).

Reference
1. Jiang, H., Wang, S., Huang, Y., He, X., Cui, H., Zhu, X., & Zheng, Y. (2015) Phase transition of spindle-associated protein regulate spindle apparatus assembly. Cell, 163(1), 108-122. PMID: 26388440


There are 34 genes.  Reviewed (0 or Unreviewed (34

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Anc-3928
ENSACAG00000002503.3
G1KAT5
CDC6
2
LLPS-Anc-1556
ENSACAG00000001643.2
G1K9N9
CHAMP1
3
LLPS-Anc-1179
ENSACAG00000016806.3
G1KT45
ckap2
4
LLPS-Anc-1944
ENSACAG00000029651.1
R4GAR9
CKAP5
5
LLPS-Anc-3987
ENSACAG00000006285.2
H9GB80
CLTB
6
LLPS-Anc-0226
ENSACAG00000016265.3
H9GN25
DLGAP5
7
LLPS-Anc-0953
ENSACAG00000006159.3
H9GBA2
DPYSL2
8
LLPS-Anc-3148
ENSACAG00000007799.2
H9GD22
DYRK3
9
LLPS-Anc-0596
ENSACAG00000006029.3
H9GAW5
GPSM2
10
LLPS-Anc-1199
ENSACAG00000013026.3
G1KN52
haus3
11
LLPS-Anc-2768
ENSACAG00000014239.3
G1KPN7
KAT14
12
LLPS-Anc-0925
ENSACAG00000006866.2
H9GC22
KATNA1
13
LLPS-Anc-0046
ENSACAG00000006621.3
H9GBQ6
KIF11
14
LLPS-Anc-2403
ENSACAG00000005488.3
H9GAB9
LOC100552827
15
LLPS-Anc-2247
ENSACAG00000017949.3
H9GPW3
LOC100554849
16
LLPS-Anc-0417
ENSACAG00000013167.3
G1KNC6
MAD2L1
17
LLPS-Anc-1458
ENSACAG00000001922.2
H9G5S7
MAPK6
18
LLPS-Anc-0120
ENSACAG00000009894.3
H9GFS5
MAPRE1
19
LLPS-Anc-1553
ENSACAG00000003046.2
G1KBF5
MARVELD1
20
LLPS-Anc-1259
ENSACAG00000001870.3
G1K9Z6
mknk1
21
LLPS-Anc-3885
ENSACAG00000003659.3
H9G7Z0
MSN
22
LLPS-Anc-0706
ENSACAG00000000242.3
H9G3T4
MTOR
23
LLPS-Anc-1943
ENSACAG00000006579.3
G1KFJ4
mtus1
24
LLPS-Anc-2714
ENSACAG00000014932.3
H9GLR4
NCOA4
25
LLPS-Anc-0973
ENSACAG00000000686.3
G1K955
PARD3
26
LLPS-Anc-3212
ENSACAG00000001369.3
H9G542
RANBP10
27
LLPS-Anc-2224
ENSACAG00000003012.3
H9G702
RBPMS
28
LLPS-Anc-1937
ENSACAG00000001408.2
G1K9J0
SEPT2
29
LLPS-Anc-0623
ENSACAG00000015557.3
G1KRH8
SMC3
30
LLPS-Anc-0293
ENSACAG00000007922.3
G1KHB8
SUN2
31
LLPS-Anc-3662
ENSACAG00000009892.3
G1KJG3
TADA3
32
LLPS-Anc-1932
ENSACAG00000001452.3
H9G5J7
TPR
33
LLPS-Anc-0439
ENSACAG00000026280.1
H9GR07
ZBTB4
34
LLPS-Anc-3816
ENSACAG00000009864.3
H9GFU0
ZNF207