Amborella trichopoda      Spindle apparatus


※ Spindle apparatus introduction

    The spindle is an important structure when cells divide. Phase separation promotes the concentration of molecules into the droplets, thereby promoting biochemical reactions. Some protein mixtures undergo a phase change to form droplets that concentrate actin to promote F-actin assembly in vitro. In addition, studies have shown that the phase transition of spindle regulatory protein BuGZ concentrates tubulin and promotes MT polymerizationbinds to tubulin and promotes spindle assembly (1).

Reference
1. Jiang, H., Wang, S., Huang, Y., He, X., Cui, H., Zhu, X., & Zheng, Y. (2015) Phase transition of spindle-associated protein regulate spindle apparatus assembly. Cell, 163(1), 108-122. PMID: 26388440


There are 21 genes.  Reviewed (0 or Unreviewed (21

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Amt-1731
AMTR_s00001p00229590
W1NM73
AMTR_s00001p00229590
2
LLPS-Amt-2265
AMTR_s00002p00029100
W1NTP8
AMTR_s00002p00029100
3
LLPS-Amt-0924
AMTR_s00005p00187660
W1PI60
AMTR_s00005p00187660
4
LLPS-Amt-1725
AMTR_s00009p00258510
W1NIR4
AMTR_s00009p00258510
5
LLPS-Amt-1395
AMTR_s00011p00256770
W1NG44
AMTR_s00011p00256770
6
LLPS-Amt-1635
AMTR_s00022p00055260
W1PVW2
AMTR_s00022p00055260
7
LLPS-Amt-1379
AMTR_s00027p00148580
W1PRT8
AMTR_s00027p00148580
8
LLPS-Amt-1332
AMTR_s00029p00198810
W1PPC1
AMTR_s00029p00198810
9
LLPS-Amt-1811
AMTR_s00029p00230900
W1PPV7
AMTR_s00029p00230900
10
LLPS-Amt-1095
AMTR_s00040p00225910
W1PY75
AMTR_s00040p00225910
11
LLPS-Amt-1923
AMTR_s00049p00193100
W1PZG5
AMTR_s00049p00193100
12
LLPS-Amt-0252
AMTR_s00056p00211180
U5D1H3
AMTR_s00056p00211180
13
LLPS-Amt-1897
AMTR_s00060p00033670
W1NKT5
AMTR_s00060p00033670
14
LLPS-Amt-2331
AMTR_s00061p00037320
U5D079
AMTR_s00061p00037320
15
LLPS-Amt-1639
AMTR_s00062p00210120
U5D282
AMTR_s00062p00210120
16
LLPS-Amt-0963
AMTR_s00069p00190170
U5D1H0
AMTR_s00069p00190170
17
LLPS-Amt-1007
AMTR_s00071p00153630
U5DBU3
AMTR_s00071p00153630
18
LLPS-Amt-0167
AMTR_s00077p00124730
W1P9E5
AMTR_s00077p00124730
19
LLPS-Amt-0321
AMTR_s00077p00193670
W1PBC5
AMTR_s00077p00193670
20
LLPS-Amt-0123
AMTR_s00117p00036240
W1NR03
AMTR_s00117p00036240
21
LLPS-Amt-0631
AMTR_s00122p00082000
W1NMD1
KATNA1