Ursus maritimus      Sam68 nuclear body


※ Sam68 nuclear body introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Sam68 nuclear bodies (SNBs) is a kind of these bodies located in Nucleus, Its component of Nucleic acids or RNPs are Chloroplast-specific mRNAs Long non-coding RNA, and it is related to mRNAs trafficking through the nucleus (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID:27838525


There are 11 genes.  Reviewed (0 or Unreviewed (11

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Urm-3417
ENSUMAG00000015788.1
A0A384D809
HNRNPA1
2
LLPS-Urm-1828
ENSUMAG00000008685.1
A0A384C9L6
HNRNPD
3
LLPS-Urm-2140
ENSUMAG00000004818.1
A0A384CHZ0
HNRNPK
4
LLPS-Urm-1465
ENSUMAG00000008568.1
A0A384CE72
KHDRBS1
5
LLPS-Urm-2224
ENSUMAG00000018593.1
A0A384C690
KHDRBS2
6
LLPS-Urm-0468
ENSUMAG00000002010.1
A0A384BJU7
KHDRBS3
7
LLPS-Urm-1004
ENSUMAG00000007842.1
A0A384C3T6
LOC103663602
8
LLPS-Urm-0870
ENSUMAG00000021133.1
A0A384DQ75
MAK16
9
LLPS-Urm-1944
ENSUMAG00000014789.1
A0A384DP50
NGDN
10
LLPS-Urm-2545
ENSUMAG00000010650.1
A0A384CYA7
RBMX
11
LLPS-Urm-3780
ENSUMAG00000009457.1
A0A384DIN9
TLE3