Pongo abelii      Sam68 nuclear body


※ Sam68 nuclear body introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Sam68 nuclear bodies (SNBs) is a kind of these bodies located in Nucleus, Its component of Nucleic acids or RNPs are Chloroplast-specific mRNAs Long non-coding RNA, and it is related to mRNAs trafficking through the nucleus (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID:27838525


There are 13 genes.  Reviewed (0 or Unreviewed (13

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Poa-0715
ENSPPYG00000029598.1
K7EVT6
2
LLPS-Poa-1891
ENSPPYG00000015533.2
A0A0A0MXR7
3
LLPS-Poa-3939
ENSPPYG00000004746.1
H2NHZ3
4
LLPS-Poa-0687
ENSPPYG00000014885.1
H2PDR7
HNRNPD
5
LLPS-Poa-2757
ENSPPYG00000019327.2
Q5R5H8
HNRNPK
6
LLPS-Poa-0783
ENSPPYG00000009945.2
H2NYQ2
HNRNPL
7
LLPS-Poa-0311
ENSPPYG00000001605.2
H2N863
KHDRBS1
8
LLPS-Poa-3279
ENSPPYG00000018899.2
K7ET18
KHDRBS3
9
LLPS-Poa-2577
ENSPPYG00000018501.2
H2PQ12
MAK16
10
LLPS-Poa-0914
ENSPPYG00000005670.2
K7ETI0
NGDN
11
LLPS-Poa-2078
ENSPPYG00000020771.2
H2PWY1
RBMX
12
LLPS-Poa-1902
ENSPPYG00000006602.2
H2NNM3
TLE3
13
LLPS-Poa-0537
ENSPPYG00000014726.2
H2PDA1
YTHDC1