Otolemur garnettii      Sam68 nuclear body


※ Sam68 nuclear body introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Sam68 nuclear bodies (SNBs) is a kind of these bodies located in Nucleus, Its component of Nucleic acids or RNPs are Chloroplast-specific mRNAs Long non-coding RNA, and it is related to mRNAs trafficking through the nucleus (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID:27838525


There are 12 genes.  Reviewed (0 or Unreviewed (12

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Otg-2085
ENSOGAG00000031414.1
H0XQW7
2
LLPS-Otg-1837
ENSOGAG00000004075.2
H0WP41
HNRNPD
3
LLPS-Otg-0362
ENSOGAG00000007478.2
H0WWD7
HNRNPK
4
LLPS-Otg-2709
ENSOGAG00000013331.2
H0X8V5
HNRNPL
5
LLPS-Otg-1112
ENSOGAG00000004582.2
H0WQ76
KHDRBS1
6
LLPS-Otg-1938
ENSOGAG00000015071.2
H0XCH5
KHDRBS2
7
LLPS-Otg-2485
ENSOGAG00000005150.2
H0WRF6
KHDRBS3
8
LLPS-Otg-2124
ENSOGAG00000024416.1
H0Y106
MAK16
9
LLPS-Otg-1615
ENSOGAG00000008735.2
H0WZ42
NGDN
10
LLPS-Otg-2624
ENSOGAG00000007839.2
H0WX61
RBMX
11
LLPS-Otg-0258
ENSOGAG00000004789.2
H0WQP3
TLE3
12
LLPS-Otg-2911
ENSOGAG00000003362.2
H0WMM2
YTHDC1