Oryzias latipes      Sam68 nuclear body


※ Sam68 nuclear body introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Sam68 nuclear bodies (SNBs) is a kind of these bodies located in Nucleus, Its component of Nucleic acids or RNPs are Chloroplast-specific mRNAs Long non-coding RNA, and it is related to mRNAs trafficking through the nucleus (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID:27838525


There are 11 genes.  Reviewed (0 or Unreviewed (11

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Orl-1928
ENSORLG00000010165.2
A0A3B3I1G9
khdrbs2
2
LLPS-Orl-1494
ENSORLG00000013441.2
H2ME53
KHDRBS3
3
LLPS-Orl-0840
ENSORLG00000010552.2
H2M469
LOC100049345
4
LLPS-Orl-1121
ENSORLG00000000486.2
H2L4A3
LOC101166731
5
LLPS-Orl-0621
ENSORLG00000004704.2
A0A3B3HAV6
LOC101167466
6
LLPS-Orl-1994
ENSORLG00000001833.2
H2L8V3
LOC101171014
7
LLPS-Orl-0798
ENSORLG00000020884.2
A0A3B3HBQ9
LOC101174409
8
LLPS-Orl-2939
ENSORLG00000019058.2
H2MXT9
mak16
9
LLPS-Orl-0394
ENSORLG00000006124.2
H2LNR9
ngdn
10
LLPS-Orl-3633
ENSORLG00000001969.2
H2L9B1
TLE3 (1 of many)
11
LLPS-Orl-1551
ENSORLG00000030544.1
A0A3B3IAV4
ythdc1