Ornithorhynchus anatinus      Sam68 nuclear body


※ Sam68 nuclear body introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Sam68 nuclear bodies (SNBs) is a kind of these bodies located in Nucleus, Its component of Nucleic acids or RNPs are Chloroplast-specific mRNAs Long non-coding RNA, and it is related to mRNAs trafficking through the nucleus (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID:27838525


There are 9 genes.  Reviewed (0 or Unreviewed (9

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Ora-0800
ENSOANG00000014119.3
F6VM68
2
LLPS-Ora-2339
ENSOANG00000012357.2
F7FFZ2
3
LLPS-Ora-1911
ENSOANG00000001932.3
F6Z5S3
HNRNPD
4
LLPS-Ora-2265
ENSOANG00000014612.3
F7EHL0
HNRNPK
5
LLPS-Ora-0303
ENSOANG00000001626.3
F7EJU6
LOC100081724
6
LLPS-Ora-0239
ENSOANG00000002395.5
F6RV49
MAK16
7
LLPS-Ora-0887
ENSOANG00000013060.3
F7A2Y0
NGDN
8
LLPS-Ora-3509
ENSOANG00000011670.3
F6RAJ0
RBMX
9
LLPS-Ora-2419
ENSOANG00000014398.3
F6UK85
YTHDC1