Oreochromis niloticus      Sam68 nuclear body


※ Sam68 nuclear body introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Sam68 nuclear bodies (SNBs) is a kind of these bodies located in Nucleus, Its component of Nucleic acids or RNPs are Chloroplast-specific mRNAs Long non-coding RNA, and it is related to mRNAs trafficking through the nucleus (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID:27838525


There are 10 genes.  Reviewed (0 or Unreviewed (10

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Orn-1163
ENSONIG00000008106.1
I3JMW6
2
LLPS-Orn-1495
ENSONIG00000007705.1
I3JLG7
3
LLPS-Orn-1347
ENSONIG00000015390.1
I3KE15
hnrnpd
4
LLPS-Orn-1333
ENSONIG00000009755.1
I3JTQ8
khdrbs2
5
LLPS-Orn-2453
ENSONIG00000007652.1
I3JL99
KHDRBS3
6
LLPS-Orn-0518
ENSONIG00000011799.1
I3K158
LOC100698882
7
LLPS-Orn-3005
ENSONIG00000015848.1
I3KFQ6
LOC100701928
8
LLPS-Orn-0161
ENSONIG00000007565.1
I3JKZ3
LOC100706673
9
LLPS-Orn-1019
ENSONIG00000000560.1
I3IVS1
mak16
10
LLPS-Orn-2852
ENSONIG00000015480.1
I3KED5
TLE3 (1 of many)