Myotis lucifugus      Sam68 nuclear body


※ Sam68 nuclear body introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Sam68 nuclear bodies (SNBs) is a kind of these bodies located in Nucleus, Its component of Nucleic acids or RNPs are Chloroplast-specific mRNAs Long non-coding RNA, and it is related to mRNAs trafficking through the nucleus (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID:27838525


There are 13 genes.  Reviewed (0 or Unreviewed (13

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Myl-3099
ENSMLUG00000000648.2
L7N0Y9
HNRNPA1
2
LLPS-Myl-3549
ENSMLUG00000010628.2
G1PGD2
HNRNPD
3
LLPS-Myl-3628
ENSMLUG00000005871.2
G1P5R3
HNRNPK
4
LLPS-Myl-1850
ENSMLUG00000000961.2
G1NUI2
HNRNPL
5
LLPS-Myl-2343
ENSMLUG00000008109.2
G1PAS3
KHDRBS1
6
LLPS-Myl-1124
ENSMLUG00000005484.2
G1P4V6
KHDRBS2
7
LLPS-Myl-3309
ENSMLUG00000004054.2
G1P1J9
KHDRBS3
8
LLPS-Myl-0755
ENSMLUG00000002758.2
G1NYL1
MAK16
9
LLPS-Myl-2477
ENSMLUG00000017232.2
G1PWE2
NGDN
10
LLPS-Myl-1618
ENSMLUG00000013209.2
G1PMA0
RBMX
11
LLPS-Myl-3312
ENSMLUG00000010603.2
G1PGA9
SMN1
12
LLPS-Myl-2016
ENSMLUG00000002275.2
G1NXH9
TLE3
13
LLPS-Myl-2583
ENSMLUG00000016300.2
G1PUB1
YTHDC1