Meleagris gallopavo      Sam68 nuclear body


※ Sam68 nuclear body introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Sam68 nuclear bodies (SNBs) is a kind of these bodies located in Nucleus, Its component of Nucleic acids or RNPs are Chloroplast-specific mRNAs Long non-coding RNA, and it is related to mRNAs trafficking through the nucleus (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID:27838525


There are 7 genes.  Reviewed (0 or Unreviewed (7

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Meg-1589
ENSMGAG00000007630.2
H9H1A1
2
LLPS-Meg-2456
ENSMGAG00000003921.2
G1MXS7
3
LLPS-Meg-2253
ENSMGAG00000008051.1
G1N7M9
HNRNPD
4
LLPS-Meg-1467
ENSMGAG00000004455.2
G1MZ53
KHDRBS1
5
LLPS-Meg-1544
ENSMGAG00000001635.2
G1MS77
MAK16
6
LLPS-Meg-0961
ENSMGAG00000010249.2
G1NCX8
TLE3
7
LLPS-Meg-2373
ENSMGAG00000010391.2
G1NDA3
YTHDC1