Macaca nemestrina      Sam68 nuclear body


※ Sam68 nuclear body introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Sam68 nuclear bodies (SNBs) is a kind of these bodies located in Nucleus, Its component of Nucleic acids or RNPs are Chloroplast-specific mRNAs Long non-coding RNA, and it is related to mRNAs trafficking through the nucleus (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID:27838525


There are 13 genes.  Reviewed (0 or Unreviewed (13

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Man-0825
ENSMNEG00000035094.1
A0A2K6CHC9
2
LLPS-Man-1460
ENSMNEG00000039542.1
A0A2K6D9K8
3
LLPS-Man-4486
ENSMNEG00000033588.1
A0A2K6C7A0
4
LLPS-Man-2758
ENSMNEG00000042992.1
A0A2K6DWA3
HNRNPA1
5
LLPS-Man-3936
ENSMNEG00000028199.1
A0A2K6B796
HNRNPD
6
LLPS-Man-0590
ENSMNEG00000044879.1
A0A2K6E9E8
HNRNPK
7
LLPS-Man-0141
ENSMNEG00000035607.1
A0A2K6CKD2
KHDRBS1
8
LLPS-Man-2523
ENSMNEG00000042875.1
A0A2K6DVF3
KHDRBS2
9
LLPS-Man-4010
ENSMNEG00000038285.1
A0A2K6D123
KHDRBS3
10
LLPS-Man-0192
ENSMNEG00000035461.1
A0A2K6CJB6
MAK16
11
LLPS-Man-0400
ENSMNEG00000038334.1
A0A2K6D1E2
NGDN
12
LLPS-Man-2349
ENSMNEG00000036112.1
A0A2K6CS58
TLE3
13
LLPS-Man-1386
ENSMNEG00000033751.1
A0A2K6C8G6
YTHDC1