Macaca mulatta      Sam68 nuclear body


※ Sam68 nuclear body introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Sam68 nuclear bodies (SNBs) is a kind of these bodies located in Nucleus, Its component of Nucleic acids or RNPs are Chloroplast-specific mRNAs Long non-coding RNA, and it is related to mRNAs trafficking through the nucleus (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID:27838525


There are 9 genes.  Reviewed (0 or Unreviewed (9

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Mam-0839
ENSMMUG00000018871.3
F6VJH6
HNRNPK
2
LLPS-Mam-0499
ENSMMUG00000004877.3
F7AN89
HNRNPL
3
LLPS-Mam-2742
ENSMMUG00000023438.3
F7F4N3
KHDRBS1
4
LLPS-Mam-0214
ENSMMUG00000030594.2
F7E0K1
LOC708538
5
LLPS-Mam-3244
ENSMMUG00000012989.3
F7HT55
LOC711588
6
LLPS-Mam-2372
ENSMMUG00000010244.3
F6QME5
MAK16
7
LLPS-Mam-1281
ENSMMUG00000014766.3
F7G0P4
NGDN
8
LLPS-Mam-1844
ENSMMUG00000014023.3
A0A1D5R774
TLE3
9
LLPS-Mam-1038
ENSMMUG00000002265.3
A0A1D5QQM9
YTHDC1