Latimeria chalumnae      Sam68 nuclear body


※ Sam68 nuclear body introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Sam68 nuclear bodies (SNBs) is a kind of these bodies located in Nucleus, Its component of Nucleic acids or RNPs are Chloroplast-specific mRNAs Long non-coding RNA, and it is related to mRNAs trafficking through the nucleus (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID:27838525


There are 10 genes.  Reviewed (0 or Unreviewed (10

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Lac-1966
ENSLACG00000013754.2
H3B152
HNRNPA1
2
LLPS-Lac-1325
ENSLACG00000005306.2
H3A8K6
HNRNPD
3
LLPS-Lac-2142
ENSLACG00000005638.1
H3A9N4
HNRNPK
4
LLPS-Lac-3220
ENSLACG00000000880.1
H2ZUB3
KHDRBS3
5
LLPS-Lac-2748
ENSLACG00000018662.1
H3BH70
LOC102348288
6
LLPS-Lac-1454
ENSLACG00000009808.1
H3ANC5
LOC102361814
7
LLPS-Lac-0292
ENSLACG00000018758.1
H3BHH6
MAK16
8
LLPS-Lac-1599
ENSLACG00000005765.1
H3AA34
NGDN
9
LLPS-Lac-2056
ENSLACG00000007395.1
H3AFD2
TLE3
10
LLPS-Lac-0495
ENSLACG00000004893.1
H3A783
YTHDC1