Gallus gallus      Sam68 nuclear body


※ Sam68 nuclear body introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Sam68 nuclear bodies (SNBs) is a kind of these bodies located in Nucleus, Its component of Nucleic acids or RNPs are Chloroplast-specific mRNAs Long non-coding RNA, and it is related to mRNAs trafficking through the nucleus (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID:27838525


There are 10 genes.  Reviewed (0 or Unreviewed (10

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Gaga-1249
ENSGALG00000008120.7
A0A1D5PVL6
2
LLPS-Gaga-2197
ENSGALG00000011184.7
3
LLPS-Gaga-2530
ENSGALG00000043929.2
A0A1L1RMH8
4
LLPS-Gaga-2150
ENSGALG00000040086.3
A0A1D5PXG0
HNRNPK
5
LLPS-Gaga-2029
ENSGALG00000003272.6
F1NLF2
KHDRBS1
6
LLPS-Gaga-3160
ENSGALG00000016276.6
E1BVW8
KHDRBS2
7
LLPS-Gaga-2638
ENSGALG00000031519.3
A0A1D5NXQ0
KHDRBS3
8
LLPS-Gaga-0738
ENSGALG00000001663.6
E1BX01
MAK16
9
LLPS-Gaga-0804
ENSGALG00000002430.7
Q98SU9
SMN
10
LLPS-Gaga-1066
ENSGALG00000035906.3
A0A1D5PEE5
YTHDC1