Felis catus      Sam68 nuclear body


※ Sam68 nuclear body introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Sam68 nuclear bodies (SNBs) is a kind of these bodies located in Nucleus, Its component of Nucleic acids or RNPs are Chloroplast-specific mRNAs Long non-coding RNA, and it is related to mRNAs trafficking through the nucleus (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID:27838525


There are 13 genes.  Reviewed (0 or Unreviewed (13

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Fec-1081
ENSFCAG00000010150.4
M3X7W8
HNRNPA1
2
LLPS-Fec-2493
ENSFCAG00000027404.3
A0A337SSS9
HNRNPD
3
LLPS-Fec-1129
ENSFCAG00000014862.5
M3WLH7
HNRNPK
4
LLPS-Fec-1740
ENSFCAG00000003183.5
A0A2I2UJ00
HNRNPL
5
LLPS-Fec-4043
ENSFCAG00000006511.5
M3W616
KHDRBS1
6
LLPS-Fec-1935
ENSFCAG00000046207.1
A0A337S6Z0
KHDRBS2
7
LLPS-Fec-3310
ENSFCAG00000000229.5
M3VUB9
KHDRBS3
8
LLPS-Fec-0171
ENSFCAG00000033972.2
A0A2I2U3N6
MAK16
9
LLPS-Fec-1981
ENSFCAG00000009093.4
M3WAS9
NGDN
10
LLPS-Fec-4544
ENSFCAG00000004779.5
M3W2U4
RBMXL1
11
LLPS-Fec-0229
ENSFCAG00000028292.3
Q8HYB8
SMN1
12
LLPS-Fec-3873
ENSFCAG00000004112.5
A0A337SKG3
TLE3
13
LLPS-Fec-1512
ENSFCAG00000026791.3
A0A2I2U960
YTHDC1