Erinaceus europaeus      Sam68 nuclear body


※ Sam68 nuclear body introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Sam68 nuclear bodies (SNBs) is a kind of these bodies located in Nucleus, Its component of Nucleic acids or RNPs are Chloroplast-specific mRNAs Long non-coding RNA, and it is related to mRNAs trafficking through the nucleus (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID:27838525


There are 5 genes.  Reviewed (0 or Unreviewed (5

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Ere-0819
ENSEEUG00000003986.1
A0A1S3AET1
KHDRBS2
2
LLPS-Ere-0602
ENSEEUG00000006280.1
A0A1S2ZAE8
MAK16
3
LLPS-Ere-0265
ENSEEUG00000011829.1
A0A1S3AKC8
NGDN
4
LLPS-Ere-0076
ENSEEUG00000015777.1
A0A1S3A984
SMN1
5
LLPS-Ere-0675
ENSEEUG00000015466.1
A0A1S3WL70
YTHDC1