Ciona savignyi      Sam68 nuclear body


※ Sam68 nuclear body introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Sam68 nuclear bodies (SNBs) is a kind of these bodies located in Nucleus, Its component of Nucleic acids or RNPs are Chloroplast-specific mRNAs Long non-coding RNA, and it is related to mRNAs trafficking through the nucleus (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID:27838525


There are 5 genes.  Reviewed (0 or Unreviewed (5

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Cis-0313
ENSCSAVG00000000472.1
H2Y680
2
LLPS-Cis-0473
ENSCSAVG00000010212.1
H2ZIC9
3
LLPS-Cis-0761
ENSCSAVG00000004912.1
H2YSD6
4
LLPS-Cis-0950
ENSCSAVG00000008390.1
H2Z9R5
5
LLPS-Cis-1000
ENSCSAVG00000005901.1
H2YXE7